Physiology of astroglia
A Verkhratsky, M Nedergaard - Physiological reviews, 2018 - journals.physiology.org
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …
[HTML][HTML] Astrocytes as guardians of neuronal excitability: mechanisms underlying epileptogenesis
QP Verhoog, L Holtman, E Aronica… - Frontiers in neurology, 2020 - frontiersin.org
Astrocytes are key homeostatic regulators in the central nervous system and play important
roles in physiology. After brain damage caused by eg, status epilepticus, traumatic brain …
roles in physiology. After brain damage caused by eg, status epilepticus, traumatic brain …
[HTML][HTML] Ion channels and electrophysiological properties of astrocytes: implications for emergent stimulation technologies
Astrocytes comprise a heterogeneous cell population characterized by distinct
morphologies, protein expression and function. Unlike neurons, astrocytes do not generate …
morphologies, protein expression and function. Unlike neurons, astrocytes do not generate …
Distinct astrocytic modulatory roles in sensory transmission during sleep, wakefulness, and arousal states in freely moving mice
Despite extensive research on astrocytic Ca2+ in synaptic transmission, its contribution to
the modulation of sensory transmission during different brain states remains largely …
the modulation of sensory transmission during different brain states remains largely …
Distribution and function of voltage-gated sodium channels in the nervous system
J Wang, SW Ou, YJ Wang - Channels, 2017 - Taylor & Francis
Voltage-gated sodium channels (VGSCs) are the basic ion channels for neuronal
excitability, which are crucial for the resting potential and the generation and propagation of …
excitability, which are crucial for the resting potential and the generation and propagation of …
AQP4 Aggravates Cognitive Impairment in Sepsis‐Associated Encephalopathy through Inhibiting Nav1.6‐Mediated Astrocyte Autophagy
DD Zhu, YL Huang, SY Guo, N Li, XW Yang… - Advanced …, 2023 - Wiley Online Library
The pathology of sepsis‐associated encephalopathy (SAE) is related to astrocyte‐
inflammation associated with aquaporin‐4 (AQP4). The aim here is to investigate the effects …
inflammation associated with aquaporin‐4 (AQP4). The aim here is to investigate the effects …
SCN3A‐Related Neurodevelopmental Disorder: A Spectrum of Epilepsy and Brain Malformation
Objective Pathogenic variants in SCN3A, encoding the voltage‐gated sodium channel
subunit Nav1. 3, cause severe childhood onset epilepsy and malformation of cortical …
subunit Nav1. 3, cause severe childhood onset epilepsy and malformation of cortical …
[HTML][HTML] Microglia and astrocytes underlie neuroinflammation and synaptic susceptibility in autism spectrum disorder
Y Xiong, Y Li - Frontiers in Neuroscience, 2023 - frontiersin.org
Autism spectrum disorder (ASD) is a common neurodevelopmental disorder with onset in
childhood. The mechanisms underlying ASD are unclear. In recent years, the role of …
childhood. The mechanisms underlying ASD are unclear. In recent years, the role of …
Ion channels and transporters in microglial function in physiology and brain diseases
Microglial cells interact with all components of the central nervous system (CNS) and are
increasingly recognized to play essential roles during brain development, homeostasis and …
increasingly recognized to play essential roles during brain development, homeostasis and …
Physiology of astroglia
Astrocytes are principal cells responsible for maintaining the brain homeostasis.
Additionally, these glial cells are also involved in homocellular (astrocyte-astrocyte) and …
Additionally, these glial cells are also involved in homocellular (astrocyte-astrocyte) and …