Проточная цитометрия в биомедицинских исследованиях
АВ Зурочка, СВ Хайдуков, ИВ Кудрявцев… - 2018 - elibrary.ru
В монографии изложены современные взгляды на применение проточной
цитофлуориметрии в норме и при различных патологических процессах. Приведена …
цитофлуориметрии в норме и при различных патологических процессах. Приведена …
Pathways mediating resolution of inflammation: when enough is too much
JN Fullerton, AJ O'Brien, DW Gilroy - The Journal of pathology, 2013 - Wiley Online Library
Patients with critical illness, and in particular sepsis, are now recognized to undergo
unifying, pathogenic disturbances of immune function. Whilst scientific and therapeutic focus …
unifying, pathogenic disturbances of immune function. Whilst scientific and therapeutic focus …
Targeted adenovirus-induced expression of IL-10 decreases thymic apoptosis and improves survival in murine sepsis
C Oberholzer, A Oberholzer… - Proceedings of the …, 2001 - National Acad Sciences
Sepsis remains a significant clinical conundrum, and recent clinical trials with anticytokine
therapies have produced disappointing results. Animal studies have suggested that …
therapies have produced disappointing results. Animal studies have suggested that …
Staphylococcus aureusα‐toxin induces apoptosis in peripheral blood mononuclear cells: role of endogenous tumour necrosis factor‐α and the mitochondrial death …
B Haslinger, K Strangfeld, G Peters… - Cellular …, 2003 - Wiley Online Library
Staphylococcus aureus infections can result in septic and toxic shock with depletion of
immune cells and massive cytokine production. Recently, we showed that, in S. aureus …
immune cells and massive cytokine production. Recently, we showed that, in S. aureus …
Novel therapeutic targets for sepsis: regulation of exaggerated inflammatory responses
Sepsis is a devastating and complex syndrome and continues to be a major cause of
morbidity and mortality among critically ill patients at the surgical intensive care unit setting …
morbidity and mortality among critically ill patients at the surgical intensive care unit setting …
Histone deacetylation inhibitors as therapy concept in sepsis
A von Knethen, B Brüne - International journal of molecular sciences, 2019 - mdpi.com
Sepsis is characterized by dysregulated gene expression, provoking a hyper-inflammatory
response occurring in parallel to a hypo-inflammatory reaction. This is often associated with …
response occurring in parallel to a hypo-inflammatory reaction. This is often associated with …
Susceptibility to programmed cell death in T-lymphocytes from septic patients: a mechanism for lymphopenia and Th2 predominance
G Roth, B Moser, C Krenn, M Brunner… - Biochemical and …, 2003 - Elsevier
Sepsis causes lymphopenia which is inversely correlated with patient survival. The role of
apoptosis-specific immune-activation and activation-induced cell-death in sepsis is …
apoptosis-specific immune-activation and activation-induced cell-death in sepsis is …
Sialic acid rescues repurified lipopolysaccharide-induced acute renal failure via inhibiting TLR4/PKC/gp91-mediated endoplasmic reticulum stress, apoptosis …
CC Yang, CA Yao, JC Yang, CT Chien - Toxicological Sciences, 2014 - academic.oup.com
Lipopolysaccharides (LPS) through Toll-like receptor 2 (TLR2) and Toll-like receptor 4
(TLR4) activation induce systemic inflammation where oxidative damage plays a key role in …
(TLR4) activation induce systemic inflammation where oxidative damage plays a key role in …
Alpha-lipoic acid attenuates oxidative damage in organs after sepsis
Sepsis progression is linked with the imbalance between reactive oxygen species and
antioxidant enzymes. Thus, the aim of this study was to evaluate the effect of alpha-lipoic …
antioxidant enzymes. Thus, the aim of this study was to evaluate the effect of alpha-lipoic …
Pathological conditions re-shape physiological Tregs into pathological Tregs
WY Yang, Y Shao, J Lopez-Pastrana, J Mai… - Burns & …, 2015 - academic.oup.com
Abstract CD4+ FOXP3+ regulatory T cells (Tregs) are a subset of CD4 T cells that play an
essential role in maintaining peripheral immune tolerance, controlling acute and chronic …
essential role in maintaining peripheral immune tolerance, controlling acute and chronic …