[HTML][HTML] Skin cancer biology and barriers to treatment: Recent applications of polymeric micro/nanostructures

NH Khan, M Mir, L Qian, M Baloch, MFA Khan… - Journal of advanced …, 2022 - Elsevier
Background Skin cancer has been the leading type of cancer worldwide. Melanoma and
non-melanoma skin cancers are now the most common types of skin cancer that have been …

Nexus between in silico and in vivo models to enhance clinical translation of nanomedicine

FM Kashkooli, M Soltani, M Souri, C Meaney… - Nano Today, 2021 - Elsevier
In cancer, one of the main barriers to effective chemotherapy is inefficient drug delivery. The
delivery of drugs to solid tumors involves various biochemical, biophysical, and mechanical …

[HTML][HTML] Iontophoresis-driven microneedle patch for the active transdermal delivery of vaccine macromolecules

Y Zheng, R Ye, X Gong, J Yang, B Liu, Y Xu… - Microsystems & …, 2023 - nature.com
COVID-19 has seriously threatened public health, and transdermal vaccination is an
effective way to prevent pathogen infection. Microneedles (MNs) can damage the stratum …

[HTML][HTML] Reactive oxygen species bridge the gap between chronic inflammation and tumor development

W Yu, Y Tu, Z Long, J Liu, D Kong, J Peng… - … medicine and cellular …, 2022 - hindawi.com
According to numerous animal studies, adverse environmental stimuli, including physical,
chemical, and biological factors, can cause low-grade chronic inflammation and subsequent …

Antibacterial and hemostatic bilayered electrospun nanofibrous wound dressings based on quaternized silicone and quaternized chitosan for wound healing

Z Gao, C Su, C Wang, Y Zhang, C Wang, H Yan… - European Polymer …, 2021 - Elsevier
The design of novel wound dressings with favorable mechanical properties, hemostasis,
inherent antibacterial function, and biocompatibility to facilitate skin wound healing and …

Research progress on cosmetic microneedle systems: Preparation, property and application

Y Huang, H Yu, L Wang, D Shen, Z Ni, S Ren… - European Polymer …, 2022 - Elsevier
Recently, the combination of cosmetology and microneedle therapy has made great
progress. Compared with direct injection, microneedles not only have functions of targeted …

Sustained release of EGF/bFGF growth factors achieved by mussel-inspired core–shell nanofibers with hemostatic and anti-inflammatory effects for promoting wound …

C Wang, Q Zhang, G Hou, C Wang, H Yan - European Polymer Journal, 2023 - Elsevier
Developing wound dressings with high-effective antibacterial activity, rapid hemostasis and
accelerated wound healing are urgently needed in clinical wound treatment. Herein, in …

[HTML][HTML] Iontophoresis of biological macromolecular drugs

M Hasan, A Khatun, K Kogure - Pharmaceutics, 2022 - mdpi.com
Over the last few decades, biological macromolecular drugs (eg, peptides, proteins, and
nucleic acids) have become a significant therapeutic modality for the treatment of various …

[HTML][HTML] NIR light-activatable dissolving microneedle system for melanoma ablation enabled by a combination of ROS-responsive chemotherapy and phototherapy

F Liu, Z Cheng, H Yi - Journal of Nanobiotechnology, 2023 - Springer
Background As a consequence of the aggressive and recurrent nature of melanoma,
repeated, multimodal treatments are often necessary to cure the disease. While microneedle …

Recent advances in 3D printed microneedles and their skin delivery application in the treatment of various diseases

R Parhi - Journal of Drug Delivery Science and Technology, 2023 - Elsevier
Microneedle (MN) has got ever-increasing attention from researchers and clinics because it
combined the advantages of both the transdermal route the and parenteral route. As a result …