[HTML][HTML] Modelling placental amino acid transfer− From transporters to placental function

RM Lewis, S Brooks, IP Crocker, J Glazier, MA Hanson… - Placenta, 2013 - Elsevier
Amino acid transfer to the fetus is dependent on several different factors. While these factors
can be understood in isolation, it is still not possible to predict the function of the system as a …

Surface-charge-induced asymmetric electrokinetic transport in confined silicon nanochannels

R Qiao, NR Aluru - Applied Physics Letters, 2005 - pubs.aip.org
Molecular dynamics simulations of a NaF solution transport in a confined silicon
nanochannel indicated that the water flux and the ionic conductivity through two oppositely …

Understanding the different cross-membrane transport kinetics of two charged molecules on the DOPG lipid surface with second harmonic generation and MD …

Y Hou, B Xu, S Chen, W Gan, Q Yuan, X Lin - Soft Matter, 2022 - pubs.rsc.org
A clear physical picture of the dynamic behavior of molecules on the surface of the lipid
membrane is highly desired and has attracted great attention from researchers. In this study …

[HTML][HTML] Computational Modelling of Paracellular Diffusion and OCT3 Mediated Transport of Metformin in the Perfused Human Placenta

EM Lofthouse, J Cleal, RM Lewis… - Journal of Pharmaceutical …, 2023 - Elsevier
Metformin is an antidiabetic drug, increasingly prescribed in pregnancy and has been
shown to cross the human placenta. The mechanisms underlying placental metformin …

Modelling the effect of intervillous flow on solute transfer based on 3D imaging of the human placental microstructure

S Perazzolo, RM Lewis, BG Sengers - Placenta, 2017 - Elsevier
Introduction A healthy pregnancy depends on placental transfer from mother to fetus.
Placental transfer takes place at the micro scale across the placental villi. Solutes from the …

[HTML][HTML] Crystallized but not soluble uric acid elicits pro-inflammatory response in short-term whole blood cultures from healthy men

H Brovold, T Lund, D Svistounov, MD Solbu… - Scientific reports, 2019 - nature.com
Several epidemiological studies have pointed at serum uric acid (SUA) as an independent
risk factor for mortality, diabetes, hypertension, cardiovascular and kidney disease; however …

[HTML][HTML] The balance of fluid and osmotic pressures across active biological membranes with application to the corneal endothelium

X Cheng, PM Pinsky - PLoS One, 2015 - journals.plos.org
The movement of fluid and solutes across biological membranes facilitates the transport of
nutrients for living organisms and maintains the fluid and osmotic pressures in biological …

Physics-based modeling for heterogeneous objects

X Qian, D Dutta - J. Mech. Des., 2003 - asmedigitalcollection.asme.org
Heterogeneous objects are composed of different constituent materials. In these objects,
material properties from different constituent materials are synthesized into one part …

Vital erythrocyte phenomena: what can theory, modeling, and simulation offer?

RJ Asaro, Q Zhu - Biomechanics and Modeling in Mechanobiology, 2020 - Springer
We overview recent advances in the theoretical modeling, in particular via numerical
simulation, of various vital human erythrocyte phenomena. The review is novel in how it …

Molecular diffusion through cyanobacterial septal junctions

M Nieves-Morión, CW Mullineaux, E Flores - MBio, 2017 - Am Soc Microbiol
Heterocyst-forming cyanobacteria grow as filaments in which intercellular molecular
exchange takes place. During the differentiation of N2-fixing heterocysts, regulators are …