Candidate biomarkers in psychiatric disorders: state of the field
The field of psychiatry is hampered by a lack of robust, reliable and valid biomarkers that can
aid in objectively diagnosing patients and providing individualized treatment …
aid in objectively diagnosing patients and providing individualized treatment …
Bipolar disorder
Bipolar disorder is a recurrent chronic disorder characterised by fluctuations in mood state
and energy. It affects more than 1% of the world's population irrespective of nationality …
and energy. It affects more than 1% of the world's population irrespective of nationality …
The role of alpha oscillations among the main neuropsychiatric disorders in the adult and developing human brain: evidence from the last 10 years of research
Alpha oscillations (7–13 Hz) are the dominant rhythm in both the resting and active brain.
Accordingly, translational research has provided evidence for the involvement of aberrant …
Accordingly, translational research has provided evidence for the involvement of aberrant …
Treatment of bipolar disorder
JR Geddes, DJ Miklowitz - The lancet, 2013 - thelancet.com
We review recent developments in the acute and long-term treatment of bipolar disorder and
identify promising future routes to therapeutic innovation. Overall, advances in drug …
identify promising future routes to therapeutic innovation. Overall, advances in drug …
EEG based Major Depressive disorder and Bipolar disorder detection using Neural Networks: A review
Mental disorders represent critical public health challenges as they are leading contributors
to the global burden of disease and intensely influence social and financial welfare of …
to the global burden of disease and intensely influence social and financial welfare of …
A critical appraisal of neuroimaging studies of bipolar disorder: toward a new conceptualization of underlying neural circuitry and a road map for future research
ML Phillips, HA Swartz - American Journal of Psychiatry, 2014 - Am Psychiatric Assoc
Objective In this critical review, the authors appraise neuroimaging findings in bipolar
disorder in emotion-processing, emotion-regulation, and reward-processing neural circuitry …
disorder in emotion-processing, emotion-regulation, and reward-processing neural circuitry …
Comparative efficacy and tolerability of pharmacological treatments in the maintenance treatment of bipolar disorder: a systematic review and network meta-analysis
Background Lithium is the established standard in the long-term treatment of bipolar
disorder, but several new drugs have been assessed for this indication. We did a network …
disorder, but several new drugs have been assessed for this indication. We did a network …
Differentiating between bipolar and unipolar depression in functional and structural MRI studies
Distinguishing depression in bipolar disorder (BD) from unipolar depression (UD) solely
based on clinical clues is difficult, which has led to the exploration of promising neural …
based on clinical clues is difficult, which has led to the exploration of promising neural …
An updated meta-analysis of oxidative stress markers in bipolar disorder
NC Brown, AC Andreazza, LT Young - Psychiatry research, 2014 - Elsevier
Despite its debilitating symptoms, the pathophysiology of bipolar disorder (BD) remains
unclear. One consistently compelling finding, however, has been the presence of oxidative …
unclear. One consistently compelling finding, however, has been the presence of oxidative …
Brain morphometric biomarkers distinguishing unipolar and bipolar depression: a voxel-based morphometry–pattern classification approach
R Redlich, JR Almeida, D Grotegerd, N Opel… - JAMA …, 2014 - jamanetwork.com
Importance The structural abnormalities in the brain that accurately differentiate unipolar
depression (UD) and bipolar depression (BD) remain unidentified. Objectives First, to …
depression (UD) and bipolar depression (BD) remain unidentified. Objectives First, to …