Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common chronic liver
disease worldwide and is strongly associated with the presence of oxidative stress …

Liver fibrosis is the most important predictor of mortality in nonalcoholic fatty liver disease
(NAFLD). Quantitative risk of mortality by fibrosis stage has not been systematically …

Hypertension, a multifactorial disorder resulting from the interplay between genetic
predisposition and environmental risk factors, affects≈ 30% of adults. Emerging evidence …

Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease which affects≈
25% of the adult population worldwide, placing a tremendous burden on human health. The …

Nonalcoholic steatohepatitis (NASH) is a progressive disease that is often accompanied by
metabolic syndrome and poses a high risk of severe liver damage. However, no effective …

In parallel with the obesity epidemic, nonalcoholic fatty liver disease (NAFLD) has emerged
as the most common chronic liver disease worldwide. Disequilibrium of lipid metabolism and …

Obesity and its associated complications are global public health concerns. Metabolic
disturbances and immune dysregulation cause adipose tissue stress and dysfunction in …

Metabolic cardiomyopathy is an emerging cause of heart failure in patients with obesity,
insulin resistance, and diabetes. It is characterized by impaired myocardial metabolic …

The innate immune system is an evolutionarily conserved system that senses and defends
against infection and irritation. Innate immune signaling is a complex cascade that quickly …

Comparative physiology studies of high-altitude species provide an exceptional opportunity
to understand naturally evolved mechanisms of hypoxia resistance. Aerobic capacity …