The purpose of this statement is to describe and define the phenotypic abnormalities that
can be identified on visual and quantitative evaluation of computed tomographic (CT) …

Rationale: Endobronchial valves (EBVs) have been successfully used in patients with
severe heterogeneous emphysema to improve lung physiology. Limited available data …

Alpha 1 antitrypsin deficiency is a hereditary condition characterized by low alpha 1
proteinase inhibitor (also known as alpha 1 antitrypsin [AAT]) serum levels. Reduced levels …

COPD is a diverse disease entity with multiple dimensions that uniquely define the patient's
performance, morbidity and mortality. FEV1 is both the traditional metric used to define the …

RATIONALE AND OBJECTIVES: Computed tomography (CT) section thickness and
reconstruction kernel each influence CT measurements of emphysema. This study was …

Rationale: Previous studies have shown associations between dust exposure or lung
burden and emphysema in coal miners, although the separate contributions of various …

Lung cancer is still the leading cause of cancer death in the world. For this reason, novel
approaches for early and more accurate diagnosis are needed. Computer-aided decision …

Rationale: Genome-wide association studies have identified genetic variants in the nicotinic
acetylcholine receptor (nAChR) on chromosome 15q24/25 as a risk for nicotine …

A pulmonary ventilation imaging technique based on four-dimensional (4D) computed
tomography (CT) has advantages over existing techniques. However, physiologically …

BACKGROUND COPD has traditionally been defined by the presence of irreversible airflow
limitation on spirometry using either the GOLD (Global Initiative for Chronic Obstructive Lung …