Cancer has become the most common cause of death in China. Owing to rapid economic
development, improved livelihood, and shifts in risk factors, cancer epidemiology has …

Although the first discovery of a non-coding RNA (ncRNA) dates back to 1958, only in recent
years has the complexity of the transcriptome started to be elucidated. However, its …

Alkylating agents are genotoxic chemicals that can induce and treat various types of cancer.
This occurs through covalent bonding with cellular macromolecules, in particular DNA …

The tobacco-specific N-nitrosamines 4-(N-nitrosomethylamino)-1-(3-pyridyl)-1-butanone
(NNK) and N′-nitrosonornicotine (NNN) always occur together and exclusively in tobacco …

There are five fibroblast growth factor receptors (FGFRs), namely, FGFR1–FGFR5. When
FGFR binds to its ligand, namely, fibroblast growth factor (FGF), it dimerizes and …

Simple Summary Genome-wide association studies have identified a vast number of cancer
risk-associated loci harboring numerous single nucleotide polymorphisms that regulate …

Cigarette smoke is a complex aerosol containing a large number of compounds with a
variety of toxicity and carcinogenicity. Long-term exposure to cigarette smoke significantly …

Background The risk of extracolonic cancer is increased in inflammatory bowel disease
(IBD) patients, but it is not clear whether there is a causal relationship. We aimed to …

Background Studying carcinogens in tobacco and nontobacco sources may be key to
understanding the pathogenesis and geographic distribution of esophageal cancer …

Lung cancer has the highest mortality rate compared to any other cancer worldwide, and
cigarette smoking is one of the major etiological factors. How cigarette smoke (CS) induces …