Plants as sources of natural and recombinant anti-cancer agents
JF Buyel - Biotechnology advances, 2018 - Elsevier
Herbal remedies were the first medicines used by humans due to the many
pharmacologically active secondary metabolites produced by plants. Some of these …
pharmacologically active secondary metabolites produced by plants. Some of these …
Emerging precision neoadjuvant systemic therapy for patients with resectable non-small cell lung cancer: current status and perspectives
LA Godoy, J Chen, W Ma, J Lally, KA Toomey… - Biomarker …, 2023 - Springer
Over the past decade, targeted therapy for oncogene-driven NSCLC and immune
checkpoint inhibitors for non-oncogene-driven NSCLC, respectively, have greatly improved …
checkpoint inhibitors for non-oncogene-driven NSCLC, respectively, have greatly improved …
The critical role of AMPK in driving Akt activation under stress, tumorigenesis and drug resistance
PI3K/Akt signaling is activated in cancers and governs tumor initiation and progression, but
how Akt is activated under diverse stresses is poorly understood. Here we identify AMPK as …
how Akt is activated under diverse stresses is poorly understood. Here we identify AMPK as …
Meta‐analysis of the difference of medians
We consider the problem of meta‐analyzing two‐group studies that report the median of the
outcome. Often, these studies are excluded from meta‐analysis because there are no well …
outcome. Often, these studies are excluded from meta‐analysis because there are no well …
Recommendations on screening for lung cancer
Canadian Task Force on Preventive Health Care - Cmaj, 2016 - Can Med Assoc
Methods The Canadian Task Force on Preventive Health Care is an independent panel of
clinicians and methodologists that makes recommendations about clinical manoeuvres …
clinicians and methodologists that makes recommendations about clinical manoeuvres …
Treatment-related toxicity in patients with early-stage non-small cell lung cancer and coexisting interstitial lung disease: a systematic review
Purpose Definitive treatment for patients with early-stage non-small cell lung cancer (ES-
NSCLC) is usually well tolerated. Patients with ES-NSCLC and coexisting interstitial lung …
NSCLC) is usually well tolerated. Patients with ES-NSCLC and coexisting interstitial lung …
One‐sample aggregate data meta‐analysis of medians
An aggregate data meta‐analysis is a statistical method that pools the summary statistics of
several selected studies to estimate the outcome of interest. When considering a continuous …
several selected studies to estimate the outcome of interest. When considering a continuous …
Survival of adults with rheumatoid arthritis associated interstitial lung disease-A systematic review and meta-analysis
HJ Farquhar, N Beckert, L Beckert, AL Edwards… - Seminars in Arthritis and …, 2023 - Elsevier
Background Rheumatoid arthritis associated interstitial lung disease (RA-ILD) is associated
with high levels of morbidity and mortality. The primary aim of this systematic review was to …
with high levels of morbidity and mortality. The primary aim of this systematic review was to …
Fighting cancer drug resistance: Opportunities and challenges for mutation-specific EGFR inhibitors
M Juchum, M Günther, SA Laufer - Drug Resistance Updates, 2015 - Elsevier
Multiple mutations in the EGFR gene are a major cause for the failure of Erlotinib and
Gefitinib in the treatment of patients harboring non-small-cell lung cancer (NSCLC) who …
Gefitinib in the treatment of patients harboring non-small-cell lung cancer (NSCLC) who …
[HTML][HTML] A primer on interstitial lung disease and thoracic radiation
CD Goodman, SFM Nijman, S Senan… - Journal of Thoracic …, 2020 - Elsevier
Interstitial lung disease (ILD) is a term used to describe a heterogeneous group of lung
disorders with characteristic clinical and imaging features. Patients with ILD are at an …
disorders with characteristic clinical and imaging features. Patients with ILD are at an …