Plants as sources of natural and recombinant anti-cancer agents

JF Buyel - Biotechnology advances, 2018 - Elsevier
Herbal remedies were the first medicines used by humans due to the many
pharmacologically active secondary metabolites produced by plants. Some of these …

Emerging precision neoadjuvant systemic therapy for patients with resectable non-small cell lung cancer: current status and perspectives

LA Godoy, J Chen, W Ma, J Lally, KA Toomey… - Biomarker …, 2023 - Springer
Over the past decade, targeted therapy for oncogene-driven NSCLC and immune
checkpoint inhibitors for non-oncogene-driven NSCLC, respectively, have greatly improved …

The critical role of AMPK in driving Akt activation under stress, tumorigenesis and drug resistance

F Han, CF Li, Z Cai, X Zhang, G Jin, WN Zhang… - Nature …, 2018 - nature.com
PI3K/Akt signaling is activated in cancers and governs tumor initiation and progression, but
how Akt is activated under diverse stresses is poorly understood. Here we identify AMPK as …

Meta‐analysis of the difference of medians

S McGrath, H Sohn, R Steele, A Benedetti - Biometrical Journal, 2020 - Wiley Online Library
We consider the problem of meta‐analyzing two‐group studies that report the median of the
outcome. Often, these studies are excluded from meta‐analysis because there are no well …

Recommendations on screening for lung cancer

Canadian Task Force on Preventive Health Care - Cmaj, 2016 - Can Med Assoc
Methods The Canadian Task Force on Preventive Health Care is an independent panel of
clinicians and methodologists that makes recommendations about clinical manoeuvres …

Treatment-related toxicity in patients with early-stage non-small cell lung cancer and coexisting interstitial lung disease: a systematic review

H Chen, S Senan, EJ Nossent, RG Boldt… - International Journal of …, 2017 - Elsevier
Purpose Definitive treatment for patients with early-stage non-small cell lung cancer (ES-
NSCLC) is usually well tolerated. Patients with ES-NSCLC and coexisting interstitial lung …

One‐sample aggregate data meta‐analysis of medians

S McGrath, XF Zhao, ZZ Qin, R Steele… - Statistics in …, 2019 - Wiley Online Library
An aggregate data meta‐analysis is a statistical method that pools the summary statistics of
several selected studies to estimate the outcome of interest. When considering a continuous …

Survival of adults with rheumatoid arthritis associated interstitial lung disease-A systematic review and meta-analysis

HJ Farquhar, N Beckert, L Beckert, AL Edwards… - Seminars in Arthritis and …, 2023 - Elsevier
Background Rheumatoid arthritis associated interstitial lung disease (RA-ILD) is associated
with high levels of morbidity and mortality. The primary aim of this systematic review was to …

Fighting cancer drug resistance: Opportunities and challenges for mutation-specific EGFR inhibitors

M Juchum, M Günther, SA Laufer - Drug Resistance Updates, 2015 - Elsevier
Multiple mutations in the EGFR gene are a major cause for the failure of Erlotinib and
Gefitinib in the treatment of patients harboring non-small-cell lung cancer (NSCLC) who …

[HTML][HTML] A primer on interstitial lung disease and thoracic radiation

CD Goodman, SFM Nijman, S Senan… - Journal of Thoracic …, 2020 - Elsevier
Interstitial lung disease (ILD) is a term used to describe a heterogeneous group of lung
disorders with characteristic clinical and imaging features. Patients with ILD are at an …