Dilated cardiomyopathy

RG Weintraub, C Semsarian, P Macdonald - The Lancet, 2017 - thelancet.com
Dilated cardiomyopathy is defined by the presence of left ventricular dilatation and
contractile dysfunction. Genetic mutations involving genes that encode cytoskeletal …

Cardiomyopathies: an overview

T Ciarambino, G Menna, G Sansone… - International journal of …, 2021 - mdpi.com
Background: Cardiomyopathies are a heterogeneous group of pathologies characterized by
structural and functional alterations of the heart. Aims: The purpose of this narrative review is …

The spectrum of epidemiology underlying sudden cardiac death

M Hayashi, W Shimizu, CM Albert - Circulation research, 2015 - Am Heart Assoc
Sudden cardiac death (SCD) from cardiac arrest is a major international public health
problem accounting for an estimated 15%–20% of all deaths. Although resuscitation rates …

Dilated cardiomyopathy: from epidemiologic to genetic phenotypes: a translational review of current literature

D Reichart, C Magnussen, T Zeller… - Journal of internal …, 2019 - Wiley Online Library
Dilated cardiomyopathy (DCM) is characterized by left ventricular dilatation and,
consecutively, contractile dysfunction. The causes of DCM are heterogeneous. DCM often …

[HTML][HTML] The landscape of genetic variation in dilated cardiomyopathy as surveyed by clinical DNA sequencing

TJ Pugh, MA Kelly, S Gowrisankar, E Hynes… - Genetics in …, 2014 - Elsevier
Purpose Dilated cardiomyopathy is characterized by substantial locus, allelic, and clinical
heterogeneity that necessitates testing of many genes across clinically overlapping …

The many faces of heart failure

D Snipelisky, SP Chaudhry… - Cardiac …, 2019 - cardiacep.theclinics.com
Heart failure (HF) is a complex, heterogeneous syndrome that results from impairment of
ventricular filling or ejection of blood associated with symptoms of dyspnea, fatigue, as well …

Potential clinical implications of miR-1 and miR-21 in heart disease and cardioprotection

B Kura, B Kalocayova, Y Devaux… - International journal of …, 2020 - mdpi.com
The interest in non-coding RNAs, which started more than a decade ago, has still not
weakened. A wealth of experimental and clinical studies has suggested the potential of non …

Murine electrophysiological models of cardiac arrhythmogenesis

CLH Huang - Physiological reviews, 2017 - journals.physiology.org
Cardiac arrhythmias can follow disruption of the normal cellular electrophysiological
processes underlying excitable activity and their tissue propagation as coherent wavefronts …

Localized structural alterations underlying a subset of unexplained sudden cardiac death

M Haïssaguerre, M Hocini, G Cheniti… - Circulation …, 2018 - Am Heart Assoc
Background: Sudden cardiac death because of ventricular fibrillation (VF) is commonly
unexplained in younger victims. Detailed electrophysiological mapping in such patients has …

T 1 and T2 mapping for early diagnosis of dilated non-ischaemic cardiomyopathy in middle-aged patients and differentiation from …

I Mordi, D Carrick, H Bezerra… - European Heart Journal …, 2016 - academic.oup.com
Aims The differential diagnosis of patients with early non-ischaemic dilated cardiomyopathy
(DCM) and those with physiological adaptation to exercise ('athlete's heart') may be difficult …