The effect of structure and preparation method on the bioactivity of polysaccharides from plants and fungi
M Yang, W Ren, G Li, P Yang, R Chen, H He - Food & Function, 2022 - pubs.rsc.org
Polysaccharides are not only the main components in the cell walls of plants and fungi, but
also a structure that supports and protects cells. In the process of obtaining polysaccharides …
also a structure that supports and protects cells. In the process of obtaining polysaccharides …
Long-acting vaccine delivery systems
Bolus vaccines are often administered multiple times due to rapid clearance and reduced
transportation to draining lymph nodes resulting in inadequate activation of T and B …
transportation to draining lymph nodes resulting in inadequate activation of T and B …
Mannose: a potential saccharide candidate in disease management
M Dhanalakshmi, D Sruthi, KR Jinuraj, K Das… - Medicinal Chemistry …, 2023 - Springer
There are a plethora of antibiotic resistance cases and humans are marching towards
another big survival test of evolution along with drastic climate change and infectious …
another big survival test of evolution along with drastic climate change and infectious …
Mannose ligands for mannose receptor targeting
M Paurević, M Šrajer Gajdošik, R Ribić - International journal of molecular …, 2024 - mdpi.com
The mannose receptor (MR, CD 206) is an endocytic receptor primarily expressed by
macrophages and dendritic cells, which plays a critical role in both endocytosis and antigen …
macrophages and dendritic cells, which plays a critical role in both endocytosis and antigen …
[HTML][HTML] Liposomal formulations of a polyleucine–antigen conjugate as therapeutic vaccines against cervical cancer
Human papilloma virus (HPV) is responsible for all cases of cervical cancer. While
prophylactic vaccines are available, the development of peptide-based vaccines as a …
prophylactic vaccines are available, the development of peptide-based vaccines as a …
Mannose-doped metal-organic frameworks induce tumor cell pyroptosis via the PERK pathway
N Jin, B Wang, X Liu, C Yin, X Li, Z Wang… - Journal of …, 2023 - Springer
Background The implementation of pyroptosis exhibits significant potential as a tactic to
enhance tumor immune microenvironments. Previous applications of pyroptosis inducers …
enhance tumor immune microenvironments. Previous applications of pyroptosis inducers …
mRNA vaccine designs for optimal adjuvanticity and delivery
Y Mochida, S Uchida - RNA biology, 2024 - Taylor & Francis
Adjuvanticity and delivery are crucial facets of mRNA vaccine design. In modern mRNA
vaccines, adjuvant functions are integrated into mRNA vaccine nanoparticles, allowing the …
vaccines, adjuvant functions are integrated into mRNA vaccine nanoparticles, allowing the …
Modified ASO conjugates encapsulated with cytidinyl/cationic lipids exhibit more potent and longer-lasting anti-HCC effects
Y Pan, J Guan, Y Gao, Y Zhu, H Li, H Guo, Q He… - … Therapy-Nucleic Acids, 2023 - cell.com
Antisense oligonucleotides (ASOs) are a class of therapeutics targeting mRNAs or genes
that have attracted much attention. However, effective delivery and optimal accumulation in …
that have attracted much attention. However, effective delivery and optimal accumulation in …
The development of surface-modified liposomes as an intranasal delivery system for group a Streptococcus vaccines
J Yang, JC Boer, M Khongkow, S Phunpee, ZG Khalil… - Vaccines, 2023 - mdpi.com
Intranasal vaccine administration can overcome the disadvantages of injectable vaccines
and present greater efficiency for mass immunization. However, the development of …
and present greater efficiency for mass immunization. However, the development of …
Current status of mannose receptor-targeted drug delivery for improved anti-HIV therapy
In the pursuit of achieving better therapeutic outcomes in the treatment of HIV, innovative
drug delivery strategies have been extensively explored. Mannose receptors, which are …
drug delivery strategies have been extensively explored. Mannose receptors, which are …