Effects of Poria cocos extract on metabolic dysfunction-associated fatty liver disease via the FXR/PPARα-SREBPs pathway

J He, Y Yang, F Zhang, Y Li, X Li, X Pu, X He… - Frontiers in …, 2022 - frontiersin.org
Despite the increase in the global prevalence of metabolic dysfunction-associated fatty liver
disease (MAFLD), no approved drug currently exists for the disease. Poria cocos (Schw.) …

TCMNPAS: a comprehensive analysis platform integrating network formulaology and network pharmacology for exploring traditional Chinese medicine

Y Liu, X Li, C Chen, N Ding, P Zheng, X Chen, S Ma… - Chinese Medicine, 2024 - Springer
The application of network formulaology and network pharmacology has significantly
advanced the scientific understanding of traditional Chinese medicine (TCM) treatment …

Metabolomics and network pharmacological analysis to explore the mechanism of ginseng treatment for spleen‐qi deficiency

M Liu, Y Cai, F Li, Y Wu, M Zhang… - Journal of …, 2022 - Wiley Online Library
Ginseng is the main Chinese herbal medicine for tonifying Qi and invigorating the spleen. It
has been used to treat spleen‐qi deficiency with good protective effects for thousands of …

Studies on the mechanism of energy metabolism via AMPK/PGC‐1α signaling pathway induced by compatibility of Ligusticum chuanxiong Hort and Gastrodia

N Ni, LP Yang, X Lin, Y Hong, L Shen - Phytotherapy Research, 2022 - Wiley Online Library
AMP‐activated protein kinase (AMPK) regulates overall energy consumption and energy
intake through cytokines. Ligusticum striatum DC (CX) combined with Gastrodia elata Blume …

Bioactive Components and Potential Mechanism Prediction of Kui Jie Kang against Ulcerative Colitis via Systematic Pharmacology and UPLC‐QE‐MS Analysis

J He, C Wan, X Li, Z Zhang, Y Yang… - Evidence‐Based …, 2022 - Wiley Online Library
Kui Jie Kang (KJK)—a traditional Chinese medicine—has demonstrated clinical therapeutic
efficacy against ulcerative colitis (UC). However, the active compounds and their underlying …

Da‐Chuan‐Xiong Decoction Ameliorates Sodium Sensitivity and Plasma Norepinephrine via Attenuation of Brain Oxidative Stress in the DOCA‐Salt Hypertensive …

Q Zhang, H Li, S Zhao, F Li… - International Journal of …, 2024 - Wiley Online Library
Background. Da‐Chuan‐Xiong Decoction (DCXD) is an aqueous extract from a classic
Chinese herbal formula composed of dried rhizomes of Ligusticum chuanxiong Hort and …

Data mining, network pharmacology, and molecular docking explore the effects of core traditional Chinese medicine prescriptions in patients with rectal cancer and qi …

S Ma, L Zheng, L Zheng, X Bian - … ‐Based Complementary and …, 2021 - Wiley Online Library
Background.“Zheng”(syndrome) is the basic unit and the basis of traditional Chinese
medicine (TCM) treatment. In clinical practice, we have been able to improve the survival …

Network Pharmacology to Clarify the Effective Substances and Their Action Mechanisms of Traditional Chinese Medicines

K Du, C Liang, Y Chang - Quality Control of Chinese Medicines: Strategies …, 2024 - Springer
Abstract Traditional Chinese medicines (TCMs) were applied to treat various biological
diseases with a long history. TCMs are characterized by multiple components corresponding …

Effects of Shugan Quzhi Capsule in treating different metabolic diseases based on network pharmacology and molecular docking

W Lin, Z Liu, L Li, Z Zhou, S Ma… - 2021 IEEE International …, 2021 - ieeexplore.ieee.org
Purpose: We explored the mechanism effects of “The Same Treatment for Different
metabolic Diseases” concept in traditional Chinese medicine (TCM). Methods: Network …