Myelin is a modified cell membrane that forms a multilayer sheath around the axon. It retains
the main characteristics of biological membranes, such as lipid bilayer, but differs from them …

Myelin basic protein (MBP) is one of the key structural elements of the myelin sheath and
has autoantigenic properties in multiple sclerosis (MS). Its intracellular interaction network is …

Slow-burning inflammation at the lesion rim is connected to the expansion of chronic
multiple sclerosis (MS) lesions. However, the underlying processes causing expansion are …

Untreated phenylketonuria (PKU) patients and PKU animal models show hypomyelination in
the central nervous system and white matter damages, which are accompanied by myelin …

Introduction Demyelination is one of the hallmarks of multiple sclerosis (MS). While
remyelination occurs during the disease, it is incomplete from the start and strongly …

In elaborating and maintaining myelin sheaths on multiple axons/segments,
oligodendrocytes distribute translation of some proteins, including myelin basic protein …

Myelin basic protein (MBP) is one of the key proteins in the development of multiple
sclerosis (MS). However, very few intracellular MBP partners have been identified up to now …

Myelin basic protein (MBP) is the second most abundant protein in the central nervous
system and is responsible for structural maintenance of the myelin sheath covering axons …

Inhibition of autophagy is one of the hallmarks of the SARS-CoV-2 infection. Recently it was
reported that SARS-CoV-2 protein ORF3a inhibits fusion of autophagosomes with …

Krabbe disease (KD) is a rare autosomal recessive disorder caused by mutations in the
galactocerebrosidase gene (GALC). Defective GALC causes aberrant metabolism of …