Vascular calcification (VC), which is categorized by intimal and medial calcification,
depending on the site (s) involved within the vessel, is closely related to cardiovascular …

Vascular calcification is associated with a significant increase in all-cause mortality and
atherosclerotic plaque rupture. Calcification has been determined to be an active process …

Calciphylaxis Calciphylaxis is a life-threatening disorder characterized by occlusion of
microvessels in the subcutaneous adipose tissue and dermis. The authors outline the …

Patients with chronic kidney disease (CKD) exhibit tremendously elevated risk for
cardiovascular disease, particularly ischemic heart disease, due to premature vascular and …

Chronic kidney disease (CKD) is an inherently systemic disease that refers to a long-term
loss of kidney function. The progression of CKD has repercussions for other organs, leading …

Reducing oxidative stress stands at the center of a prevention and control strategy for
mitigating cellular senescence and aging. Kidney disease is characterized by a premature …

The association between vitamin D deficiency and especially critical shortage of active
vitamin D (1, 25-dihydroxyvitamin D, calcitriol) with the development of secondary …

Background. Calcific uraemic arteriolopathy (CUA, calciphylaxis) is a rare disease
predominantly in dialysis patients and associated with high mortality. Painful skin ulcerations …

Phosphate plays essential roles in many biological processes, and the serum phosphate
level is tightly controlled. Chronic hypophosphatemia causes impaired mineralization of the …

The physicochemical deposition of calcium-phosphate in the arterial wall is prevented by
calcification inhibitors. Studies in cohorts of patients with rare genetic diseases have shed …