Basolateral amygdala and stress-induced hyperexcitability affect motivated behaviors and addiction

BM Sharp - Translational psychiatry, 2017 - nature.com
The amygdala integrates and processes incoming information pertinent to reward and to
emotions such as fear and anxiety that promote survival by warning of potential danger …

A neuromarker for drug and food craving distinguishes drug users from non-users

L Koban, TD Wager, H Kober - Nature neuroscience, 2023 - nature.com
Craving is a core feature of substance use disorders. It is a strong predictor of substance use
and relapse and is linked to overeating, gambling, and other maladaptive behaviors …

Addictions neuroclinical assessment: a neuroscience-based framework for addictive disorders

LE Kwako, R Momenan, RZ Litten, GF Koob… - Biological …, 2016 - Elsevier
This article proposes a heuristic framework for the Addictions Neuroclinical Assessment that
incorporates key functional domains derived from the neurocircuitry of addiction. We review …

Brain gray matter structures associated with trait impulsivity: A systematic review and voxel‐based meta‐analysis

N Pan, S Wang, Y Zhao, H Lai, K Qin, J Li… - Human Brain …, 2021 - Wiley Online Library
Trait impulsivity is a multifaceted personality characteristic that contributes to maladaptive
life outcomes. Although a growing body of neuroimaging studies have investigated the …

Psychedelic therapy in the treatment of addiction: the past, present and future

R Zafar, M Siegel, R Harding, T Barba… - Frontiers in …, 2023 - frontiersin.org
Psychedelic therapy has witnessed a resurgence in interest in the last decade from the
scientific and medical communities with evidence now building for its safety and efficacy in …

Neurobiological correlates of cue-reactivity in alcohol-use disorders: A voxel-wise meta-analysis of fMRI studies

J Zeng, S Yu, H Cao, Y Su, Z Dong, X Yang - … & Biobehavioral Reviews, 2021 - Elsevier
Altered brain responses to alcohol-associated stimuli are a neural hallmark of alcohol-use
disorder (AUD) and a promising target for pharmacotherapy. However, findings in cue …

Neural substrates of cue reactivity: association with treatment outcomes and relapse

KE Courtney, JP Schacht, K Hutchison… - Addiction …, 2016 - Wiley Online Library
Given the strong evidence for neurological alterations at the basis of drug dependence,
functional magnetic resonance imaging (fMRI) represents an important tool in the clinical …

The role of stress in drug addiction. An integrative review

P Ruisoto, I Contador - Physiology & behavior, 2019 - Elsevier
Background The high prevalence and burden to society of drug abuse and addiction is
undisputed. However, its conceptualisation as a brain disease is controversial, and …

Impaired functional connectivity within and between frontostriatal circuits and its association with compulsive drug use and trait impulsivity in cocaine addiction

Y Hu, BJ Salmeron, H Gu, EA Stein, Y Yang - JAMA psychiatry, 2015 - jamanetwork.com
Importance Converging evidence has long identified both impulsivity and compulsivity as
key psychological constructs in drug addiction. Although dysregulated striatal-cortical …

Cue-reactivity in behavioral addictions: A meta-analysis and methodological considerations

K Starcke, S Antons, P Trotzke… - Journal of behavioral …, 2018 - akjournals.com
Background and aims Recent research has applied cue-reactivity paradigms to behavioral
addictions. The aim of the current meta-analysis is to systematically analyze the effects of …