Redefining fundamental concepts of transcription initiation in bacteria

C Mejía-Almonte, SJW Busby, JT Wade… - Nature Reviews …, 2020 - nature.com
Despite enormous progress in understanding the fundamentals of bacterial gene regulation,
our knowledge remains limited when compared with the number of bacterial genomes and …

Ectoines in cell stress protection: uses and biotechnological production

JM Pastor, M Salvador, M Argandoña, V Bernal… - Biotechnology …, 2010 - Elsevier
Microorganisms produce and accumulate compatible solutes aiming at protecting
themselves from environmental stresses. Among them, the wide spread in nature ectoines …

[HTML][HTML] Architecture of the Escherichia coli nucleoid

SC Verma, Z Qian, SL Adhya - PLoS genetics, 2019 - journals.plos.org
How genomes are organized within cells and how the 3D architecture of a genome
influences cellular functions are significant questions in biology. A bacterial genomic DNA …

[HTML][HTML] H-NS mediates the silencing of laterally acquired genes in bacteria

S Lucchini, G Rowley, MD Goldberg, D Hurd… - PLoS …, 2006 - journals.plos.org
Histone-like nucleoid structuring protein (H-NS) is a modular protein that is associated with
the bacterial nucleoid. We used chromatin immunoprecipitation to determine the binding …

H-NS: a universal regulator for a dynamic genome

CJ Dorman - Nature Reviews Microbiology, 2004 - nature.com
The effect of the bacterial heat-stable nucleoid-structuring (H-NS) protein on gene
expression is overwhelmingly negative and extends throughout the genome, pointing to an …

The role of nucleoid‐associated proteins in the organization and compaction of bacterial chromatin

RT Dame - Molecular microbiology, 2005 - Wiley Online Library
The bacterial chromosomal DNA is folded into a compact structure called nucleoid. The
shape and size of this 'body'is determined by a number of factors. Major players are DNA …

H-NS, the genome sentinel

CJ Dorman - Nature Reviews Microbiology, 2007 - nature.com
Two recent reports have indicated that the H-NS protein in Salmonella enterica serovar
Typhimurium has a key role in selectively silencing the transcription of large numbers of …

Anti-silencing: overcoming H-NS-mediated repression of transcription in Gram-negative enteric bacteria

DM Stoebel, A Free, CJ Dorman - Microbiology, 2008 - microbiologyresearch.org
The H-NS nucleoid-associated DNA-binding protein is an important global repressor of
transcription in Gram-negative bacteria. Recently, H-NS has been implicated in the process …

A divalent switch drives H-NS/DNA-binding conformations between stiffening and bridging modes

Y Liu, H Chen, LJ Kenney, J Yan - Genes & development, 2010 - genesdev.cshlp.org
Heat-stable nucleoid structuring protein (H-NS) is an abundant prokaryotic protein that plays
important roles in organizing chromosomal DNA and gene silencing. Two controversial …

[HTML][HTML] Genomic transcriptional response to loss of chromosomal supercoiling in Escherichia coli

BJ Peter, J Arsuaga, AM Breier, AB Khodursky… - Genome biology, 2004 - Springer
Abstract Background The chromosome of Escherichia coli is maintained in a negatively
supercoiled state, and supercoiling levels are affected by growth phase and a variety of …