Evidence supports the central role of endothelium and inflammation in all phases of the
atherosclerotic process. Clinical studies have shown their prognostic potential for the …

Although plasminogen activator inhibitor 1 (PAI-1) is one of the primary regulators of the
fibrinolytic system, it also has dramatic effects on cell adhesion, detachment and migration …

Atherosclerosis is a chronic inflammatory disease that is characterized by the development
of fibrotic plaques in the arterial wall. The disease exhibits a complex aetiology and its …

Visfatin/NAMPT (nicotinamide phosphoribosyltransferase) is a protein with several
suggested functions. Although the first discovery of this molecule as a pre-B-cell colony …

Flaxseed and its components may improve cardiovascular health because of their numerous
attributes. Flaxseed contains 35% of its mass as oil, of which 55% is α-linolenic acid (ALA) …

A considerable literature has been published on the health benefits of fish, oil-rich fish and
fish oils and their constituent long-chain (LC) n-3 PUFA. Evidence from epidemiological …

The development of atherosclerotic cardiovascular disease is a common comorbidity in
patients with the metabolic syndrome, a concurrence of cardiovascular risk factors in one …

Decreased circulating protein C and increased circulating thrombomodulin are markers of
the prothrombotic, antifibrinolytic state associated with poor outcomes in sepsis but have not …

The cysteine protease cathepsin L is one of the most potent mammalian elastases and
collagenases, widely expressed at basal levels in most tested tissues and cell types, and …

Cigarette smoking is the major cause of preventable morbidity and mortality in the United
States and constitutes a major risk factor for atherosclerotic vascular disease, including …