Background. Different soluble molecules involved in inflammation, endothelial damage, or
hemostasis are recognized as potential cardiovascular risk markers. Studies to assess the …

Biomechanical forces generated by blood flow play an important role in the pathogenesis of
vascular disease. For example, regions exposed to non-uniform shear stresses develop …

Considerable evidence indicates that patients with rheumatoid arthritis (RA) are at greater
risk of developing atherosclerosis and cardiovascular disease. Recent studies support the …

Abstract CX3CL1/Fractalkine, a chemokine specific to monocytes and NK cells, is induced
synergistically by TNF-α and IFN-γ in vascular endothelial cells. However, the mechanism …

A role of interferon-γ is suggested in early development of atherosclerosis. However, the role
of interferon-γ in progression and destabilization of advanced atherosclerotic plaques …

Among antioxidants in the human body, bilirubin has been recognized over the past 20
years to afford protection against different chronic conditions, including inflammation and …

BACKGROUND: Residual platelet reactivity (RPR) on antiplatelet therapy in ischemic heart
disease patients is associated with adverse events. Clinical, cellular and pharmacogenetic …

Foam cell formation from monocyte-derived macrophages is a hallmark of atherosclerotic
lesions. Aspects of this process can be recapitulated in vitro by exposing M-CSF-induced or …

Background The association of serum uric acid (SUA) with cardiovascular disease (CVD) is
inconsistent and limited by a single measurement of SUA. This study aimed to investigate …

Network analysis is a novel method to understand the complex pathogenesis of
inflammation-driven atherosclerosis. Using this approach, we attempted to identify key …