An effective immune response against viral infections depends on the activation of cytotoxic
T cells that can clear infection by killing virus-infected cells. Proper activation of these T cells …

During the extended clinically latent period associated with Human Immunodeficiency Virus
(HIV) infection the virus itself is far from latent. This phase of infection generally comes to an …

The rules for T‐cell‐mediated control of viruses that infect via the respiratory mucosae show
both common themes and differences depending on the nature of the pathogen. Virus …

A small subset of human immunodeficiency virus type 1 (HIV-1)-infected, therapy-naive
individuals–referred to as long-term non-progressors (LTNPs)–maintain a favourable course …

There are few reports of the natural history of human immunodeficiency virus (HIV) infection
from Asia. In a retrospective analysis of 594 patients (72.9% male; baseline CD4 cell count …

Uncertainty is an important part of the illness experience. Mishel elaborated a theory of
uncertainty in acute illness and later expanded the framework to account for uncertainty in …

Human immunodeficiency virus-associated neurological disorders (HANDs) affect the
majority of AIDS patients and are a significant problem among HIV-1-infected individuals …

Abstract Switching from IgM to IgG and IgA is essential for antiviral immunity and requires
engagement of CD40 on B cells by CD40L on CD4+ T cells. HIV-1 is thought to impair CD40 …

Background: Definitive diagnosis of tuberculous pericarditis requires isolation of the tubercle
bacillus from pericardial fluid, but isolating the organism is often difficult. Aim: To improve …

Deuterated glucose labeling was used to measure the in vivo turnover of T lymphocytes. A
realistic T cell kinetic model, with populations of resting and activated T cells, was fitted to d …