Epigenetics and blood disorders

B Scholz, R Marschalek - British journal of haematology, 2012 - Wiley Online Library
The last three decades of cancer research were guided by the hypothesis that cancer cells
evolve due to the accumulation of many genetic aberrations over time. While this is still true …

The therapy of relapsed acute leukaemia in adults

MR Litzow - Blood reviews, 2004 - Elsevier
Although the cure of acute leukaemia has improved significantly, many patients will still
relapse and die. The unraveling of the molecular pathogenesis of acute leukaemia has lead …

Treatment options in advanced myelodysplastic syndrome, with emphasis on epigenetic therapy

Y Oki, JPJ Issa - International journal of hematology, 2007 - Springer
Medical management of myelodysplastic syndrome (MDS) remains challenging, particularly
in advanced stages where the risk of developing acute leukemia is very high and the …

[HTML][HTML] 地西他滨和5-阿扎胞苷在癌症研究及临床上的应用

杨薇, 陈银海, 崔恒宓 - 2006 - journal11.magtechjournal.com
目的介绍分子印迹技术及分子印迹聚合物, 综述分子印迹聚合物在各类给药系统中的应用.
方法对近几年发表的相关论文进行全面地回顾和整理, 阐述分子印迹聚合物在药物传递系统中的 …

New molecular therapy targets in acute myeloid leukemia

U Krug, H Serve, C Müller-Tidow, RM Mesters… - Targeted Therapies in …, 2007 - Springer
Despite improvements to acute myelogenous leukemia (AML) therapy during the last 25
years, the majority of patients still succumb to the disease. Thus, there remains an urgent …

Novel agents in acute myeloid leukemia

A Aribi, F Ravandi, F Giles - The Cancer Journal, 2006 - journals.lww.com
In the past 40 years, advances in supportive care and development of chemotherapeutic
agents have led to improved outcomes in patients with acute myeloid leukemia. High …

Expression and proliferation-promoting role of lymphoid enhancer-binding factor 1 in human clear cell renal carcinoma

D Shang, R Bi, T Han, D Wang, Y Tian… - Cancer Investigation, 2014 - Taylor & Francis
Lymphoid enhancer-binding factor 1 (LEF1) has been regarded as an important gene for
carcinogenesis in many malignancies, however, the role of LEF1 in the progression of …

[引用][C] Raji 细胞Id4 基因甲基化检测及As2O3 对其甲基化影响的研究

曲凡 - 中华血液学杂志, 2010

[引用][C] 蛋白质组学技术分析5-aza-2dC 处理白血病细胞HL-60 前后的差异表达蛋白质

谭潭, 梁婷, 汤参娥, 肖艳华, 易红, 张鹏飞, 彭芳… - 国际病理科学与临床杂志, 2009

Detection method for methylation density on microarray using methyl-CpG-binding domain protein

J Luo, W Zheng, Y Wang, Z Wu, Y Bai, Z Lu - Analytical biochemistry, 2009 - Elsevier
A method for determining methylation density of target CpG islands has been established. In
the method, DNA microarray was prepared by spotting a set of PCR products amplified from …