[HTML][HTML] Obesity and cancer: the role of adipose tissue and adipo-cytokines-induced chronic inflammation

R Divella, R De Luca, I Abbate, E Naglieri… - Journal of …, 2016 - ncbi.nlm.nih.gov
Adipose tissue in addition to its ability to keep lipids is now recognized as a real organ with
both metabolic and endocrine functions. Recent studies demonstrated that in obese animals …

[HTML][HTML] Insulin resistance and oxidative stress in the brain: what's new?

M Maciejczyk, E Żebrowska, A Chabowski - International journal of …, 2019 - mdpi.com
The latest studies have indicated a strong relationship between systemic insulin resistance
(IR) and higher incidence of neurodegeneration, dementia, and mild cognitive impairment …

[HTML][HTML] β-sitosterol circumvents obesity induced inflammation and insulin resistance by down-regulating IKKβ/NF-κB and JNK signaling pathway in adipocytes of type …

S Jayaraman, N Devarajan, P Rajagopal, S Babu… - Molecules, 2021 - mdpi.com
β-sitosterol (SIT), the most abundant bioactive component of vegetable oil and other plants,
is a highly potent antidiabetic drug. Our previous studies show that SIT controls …

[HTML][HTML] Endoplasmic reticulum stress activates unfolded protein response signaling and mediates inflammation, obesity, and cardiac dysfunction: therapeutic and …

OM Amen, SD Sarker, R Ghildyal, A Arya - Frontiers in pharmacology, 2019 - frontiersin.org
Obesity has been implicated as a risk factor for insulin resistance and cardiovascular
diseases (CVDs). Although the association between obesity and CVD is a well-established …

The science behind microgreens as an exciting new food for the 21st century

U Choe, LL Yu, TTY Wang - Journal of agricultural and food …, 2018 - ACS Publications
Chronic diseases are a major health problem in the United States. Accumulated data
suggest that consumption of vegetables can significantly reduce the risk of many chronic …

[HTML][HTML] Effects of phytosomal curcumin on anthropometric parameters, insulin resistance, cortisolemia and non-alcoholic fatty liver disease indices: a double-blind …

AFG Cicero, A Sahebkar, F Fogacci, M Bove… - European journal of …, 2020 - Springer
Purpose Curcumin has shown to exert a positive impact on human glucose metabolism,
even if its bioavailability is usually very low. The present study aimed to explore the effect of …

NOD1 and NOD2 in inflammatory and infectious diseases

BC Trindade, GY Chen - Immunological reviews, 2020 - Wiley Online Library
It has been long recognized that NOD1 and NOD2 are critical players in the host immune
response, primarily by their sensing bacterial peptidoglycan‐conserved motifs. Significant …

[HTML][HTML] Wound chronicity, impaired immunity and infection in diabetic patients

N Rodríguez-Rodríguez, I Martínez-Jiménez… - MEDICC …, 2022 - SciELO Public Health
BACKGROUND Diabetic foot ulcers are a common diabetic complication leading to
alarming figures of amputation, disability, and early mortality. The diabetic glucooxidative …

Inflammation and depression in young people: a systematic review and proposed inflammatory pathways

YJ Toenders, L Laskaris, CG Davey, M Berk… - Molecular …, 2022 - nature.com
Depression onset peaks during adolescence and young adulthood. Current treatments are
only moderately effective, driving the search for novel pathophysiological mechanisms …

[HTML][HTML] Sulforaphane reduces obesity by reversing leptin resistance

I Çakır, P Lining Pan, CK Hadley, A El-Gamal… - Elife, 2022 - elifesciences.org
The ascending prevalence of obesity in recent decades is commonly associated with
soaring morbidity and mortality rates, resulting in increased health-care costs and …