Epigenetic biomarkers for disease susceptibility and preventative medicine
MK Skinner - Cell metabolism, 2024 - cell.com
The development of molecular biomarkers for disease makes it possible for preventative
medicine approaches to be considered. Therefore, therapeutics, treatments, or clinical …
medicine approaches to be considered. Therefore, therapeutics, treatments, or clinical …
[HTML][HTML] Role of Selenium in Pathogenesis and Treatment of the Autoimmune Diseases
In vitro investigations have revealed that consumption of selenium can considerably
decrease the expression of IFN-g in Th1 cells. A low plasma selenium content has been …
decrease the expression of IFN-g in Th1 cells. A low plasma selenium content has been …
[HTML][HTML] Exploring potential network pharmacology-and molecular docking-based mechanism of melittin in treating rheumatoid arthritis
L Yang, W Zhao, X Gong, D Yue, Y Liu, Y Tian, K Dong - Medicine, 2023 - journals.lww.com
Background: Rheumatoid arthritis (RA) is a type of difficult-to-cure arthralgia with a
worldwide prevalence. It severely affects people's living standards. For a long time, bee …
worldwide prevalence. It severely affects people's living standards. For a long time, bee …
Effects of bile salt-stimulated lipase on blood cells and associations with disease activity in human inflammatory joint disorders
S Lindquist, Y Wang, EL Andersson, S Tsuji Grebe… - Plos one, 2023 - journals.plos.org
The bile salt-stimulated lipase (BSSL) was originally recognized as a lipolytic enzyme
expressed by the exocrine pancreas and in some species, notably humans, the lactating …
expressed by the exocrine pancreas and in some species, notably humans, the lactating …
Synthesized pyrrole ester ameliorates adjuvant‑induced arthritis in Wistar rats by alleviating inflammation and downregulating the pro‑inflammatory cytokines
PF Kimariyo, SP Kurati, SNVD Bhargavi, A Gordon… - …, 2024 - Springer
Piperine is an amide alkaloid responsible for producing the pungent smell that comes from
black pepper. Piperine has been explained to exhibit significant properties such as anti …
black pepper. Piperine has been explained to exhibit significant properties such as anti …
Xinfeng Capsule Inhibits Pyroptosis and Ameliorates Myocardial Injury in Rats with Adjuvant Arthritis via the GAS5/miR-21/TLR4 Axis
W Fu, Y Cao, J Liu, C Huang, K Shu… - Drug Design …, 2024 - Taylor & Francis
Purpose This study probed the mechanism of action of Xinfeng Capsule (XFC) in myocardial
injury in rats with adjuvant arthritis (AA) via the growth arrest-specific transcript 5 …
injury in rats with adjuvant arthritis (AA) via the growth arrest-specific transcript 5 …
Tapinarof cream 1% once daily for the treatment of adults with mild to severe plaque psoriasis: A novel topical therapy targeting the aryl hydrocarbon receptor
AW Armstrong, JL McConaha - Journal of managed care & specialty …, 2023 - jmcp.org
Plaque psoriasis is a chronic, immunemediated skin disease characterized by scaly,
erythematous, pruritic plaques. The effects of psoriasis are often debilitating and …
erythematous, pruritic plaques. The effects of psoriasis are often debilitating and …
Vitamin D and rheumatoid arthritis
S Harrison, E Nikiphorou, L Jeffery, K Raza… - Feldman and Pike's …, 2024 - Elsevier
dihydroxyvitamin D (1, 25 (OH) 2 D) has potent immunomodulatory properties, and many
immune cells express the vitamin D receptor (VDR) and the 1α-hydroxylase (1α-OHase) …
immune cells express the vitamin D receptor (VDR) and the 1α-hydroxylase (1α-OHase) …
Association between COMMD1 gene polymorphism rs11125908 and rheumatoid arthritis in the Cuban population
MC Alvarez, AC Benitez, TD Argudin, HN Cuni… - Reumatismo, 2024 - reumatismo.org
Objective. To evaluate the association of the rs11125908 polymorphism in the COMMD1
gene in the Cuban population with rheumatoid arthritis (RA). Methods. In this case-control …
gene in the Cuban population with rheumatoid arthritis (RA). Methods. In this case-control …
[HTML][HTML] 基于网络药理学及分子对接探讨四妙汤治疗类风湿关节炎的作用机制
罗书曼， 朱星， 陈云志， 陈帅， 曾凡勇， 周艳… - Pharmacy …, 2023 - hanspub.org
目的: 基于网络药理学及分子对接探讨四妙汤治疗类风湿关节炎(rheumatoid arthritis, RA)
的潜在活性成分及可能的分子机制. 方法: 使用药理学数据库(TCMSP), 预设生物利用度(OB)≥ …
的潜在活性成分及可能的分子机制. 方法: 使用药理学数据库(TCMSP), 预设生物利用度(OB)≥ …