Dexmedetomidine (DEX) is a highly selective α2-adrenergic agonist with sedative and
analgesic properties, with minimal respiratory effects. It is used as a sedative in the intensive …

Resting state functional MRI (rs-fMRI) and functional connectivity mapping have become
widely used tools in the human neuroimaging community and their use is rapidly spreading …

The association of antihypertensive medication use with cognitive decline (including mild
cognitive impairment) or dementia (including Alzheimer's disease (AD), vascular dementia …

We tested dexmedetomidine, an α 2 agonist, for its ability to decrease heart rate, arterial
blood pressure, and neuroendocrinal responses to skull-pin head-holder application during …

Sepsis is a major cause of death and the most common cause of death among critically ill,
non-ICU patients. Dexmedetomidine (DEX), an 2 adrenergic receptor agonist, presents …

Pain management during burn dressing changes is a critical part of treatment in acute burn
injuries. Although several treatment options have been suggested, it is still a challenge in a …

Abstract Background and Objective Several clinical trials have examined and indicated the
usefulness of epidural dexmedetomidine therapy. However, there has been no systematic …

Opioid analgesic drugs Page 318 CHAPTER 12 OPIOID ANALGESIC DRUGS BUTCH
KUKANICH AND MARK G. PAPICH Introduction Background on Opioids Opioid Role in …

Analgesic therapy following intracranial procedures remains a source of concern and
controversy. Although opioids are the mainstay of the “balanced” general anesthetic …

Abstract Dexmedetomidine (Dexdor or Precedex®) is considered as a sedative agent which
is widely used as an adjuvant in general anesthesia and critical care practice. There is …