The metabolism of cancer has been an interesting hallmark and metabolic reprogramming,
especially the change from oxidative phosphorylation in mitochondria to glucose …

Digestive tract endoscopy is a common procedure that takes place outside the operating
room most of the time and has become more and more complex due to advanced invasive …

Background Retrospective studies of patients undergoing cancer surgery suggest the use of
local anesthesia may decrease tumor recurrence and improve survival. The mechanisms on …

Background Retrospective analysis and pre-clinical studies suggest that local anesthetics
have anti-tumoral effects. However, the association between cancer recurrence and the use …

Abstract Background Local anesthetic Bupivacaine commonly used in gastric cancer
resection operation has been reported to suppress the progression of gastric cancer …

Esophageal stricture is a severe adverse event after circumferential endoscopic submucosal
dissection (ESD). Steroid administration is a new method to prevent stricture formation. We …

Background Post-operative pain of endoscopic submucosal dissection (ESD) is always be
overlooked and undertreated by endoscopists. However, the incidence of moderate to …

Non-small cell lung cancer (NSCLC) is a prevalent malignancy with high mortality and poor
prognosis. Bupivacaine serves as a widely used local anesthetic and presents potential anti …

Endoscopic submucosal dissection (ESD) is an advanced therapy for early gastric neoplasm
and requires sedation with adequate analgesia. Lidocaine is a short-acting local anesthetic …

To probe into the impact of Bupivacaine on colorectal cancer (CRC) proliferation, apoptosis,
and autophagy through regulating the NF-κB signaling pathway. Our work treated CRC cells …