Structural hippocampal abnormalities are common in many neurological and psychiatric
disorders, and variation in hippocampal measures is related to cognitive performance and …

Disrupted hippocampal performance underlies psychiatric comorbidities and cognitive
impairments in patients with neurodegenerative disorders. To understand the contribution of …

Introduction Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder associated
with cognitive and behavioral impairments and motor symptoms. Magnetic resonance …

Motor neuron disease is an umbrella term encompassing a multitude of clinically
heterogeneous phenotypes. The early and accurate categorisation of patients is hugely …

The description of group-level, genotype-and phenotype-associated imaging traits is
academically important, but the practical demands of clinical neurology centre on the …

Amyotrophic lateral sclerosis (ALS) is associated with considerable clinical heterogeneity
spanning from diverse disability profiles, differences in UMN/LMN involvement, divergent …

Temporal lobe studies in motor neuron disease overwhelmingly focus on white matter
alterations and cortical grey matter atrophy. Reports on amygdala involvement are …

Objective To understand the progressive nature of amyotrophic lateral sclerosis (ALS) by
investigating differential brain patterns of gray and white matter involvement in clinically or …

Primary lateral sclerosis (PLS) is classically considered a 'pure'upper motor neuron disorder.
Motor cortex atrophy and pyramidal tract degeneration are thought to be pathognomonic of …

Background: Magnetic resonance spectroscopy (MRS) in amyotrophic lateral sclerosis
(ALS) has been overwhelmingly applied to motor regions to date and our understanding of …