A physiological level of oxygen/nitrogen free radicals and non-radical reactive species
(collectively known as ROS/RNS) is termed oxidative eustress or “good stress” and is …

Abstract Purpose of Review Atherosclerosis is now considered a chronic inflammatory
disease. Oxidative stress induced by generation of excess reactive oxygen species has …

Nitric oxide (NO) is a small free radical with critical signaling roles in physiology and
pathophysiology. The generation of sufficient NO levels to regulate the resistance of the …

Myeloperoxidase (MPO) is a member of the superfamily of heme peroxidases that is mainly
expressed in neutrophils and monocytes. MPO-derived reactive species play a key role in …

Significance: Oxidative stress is considered to be an important component of various
diseases. A vast number of methods have been developed and used in virtually all diseases …

Hypercholesterolaemia leads to cholesterol accumulation in macrophages and other
immune cells, which promotes inflammatory responses, including augmentation of Toll-like …

High-density lipoproteins (HDLs) protect against atherosclerosis by removing excess
cholesterol from macrophages through the ATP-binding cassette transporter A1 (ABCA1) …

Nowadays, it is known that oxidative stress plays at least two roles within the cell, the
generation of cellular damage and the involvement in several signaling pathways in its …

Based on the “free radical theory” of disease, researchers have been trying to elucidate the
role of oxidative stress from free radicals in cardiovascular disease. Considerable data …

Atherosclerosis is a chronic progressive disease that involves damage to the intima,
inflammatory cell recruitment and the accumulation of lipids followed by calcification and …