[HTML][HTML] The role of immune mechanisms in abdominal aortic aneurysm: could it be a promising therapeutic strategy?

R Dinc - Acta Cardiologica Sinica, 2023 - ncbi.nlm.nih.gov
Abdominal aortic aneurysm (AAA) is an enlargement of the aorta greater than 50% in
diameter. Although up to 80% of cases result in mortality if the aneurysm ruptures, patients …

The future for the therapeutics of abdominal aortic aneurysm: engineered nanoparticles drug delivery for abdominal aortic aneurysm

P Du, Y Hou, C Su, J Gao, Y Yang, J Zhang… - … in Bioengineering and …, 2024 - frontiersin.org
Abdominal aortic aneurysm (AAA) is a severe cardiovascular disease with a high mortality
rate. Several screening and diagnostic methods have been developed for AAA early …

Effect of Hydralazine on Angiotensin II-Induced Abdominal Aortic Aneurysm in Apolipoprotein E-Deficient Mice

Y Wang, O Sargisson, DT Nguyen, K Parker… - International Journal of …, 2023 - mdpi.com
The rupture of an abdominal aortic aneurysm (AAA) causes about 200,000 deaths
worldwide each year. However, there are currently no effective drug therapies to prevent …

The SNP rs4591246 in pri-miR-1-3p is associated with abdominal aortic aneurysm risk by regulating cell phenotypic transformation via the miR-1-3p/TLR4 axis

T Li, J Jing, L Sun, Y Gong, J Yang, C Ma… - International …, 2023 - Elsevier
Emerging evidence reveals that single nucleotide polymorphism (SNP) within miRNAs can
affect the risk of cardiovascular diseases. However, the role of miRNA SNPs in abdominal …

A highly selective mPGES-1 inhibitor to block abdominal aortic aneurysm progression in the angiotensin mouse model

LM Weaver, MJ Stewart, K Ding, CD Loftin, F Zheng… - Scientific Reports, 2024 - nature.com
Abdominal aortic aneurysm (AAA) is a deadly, permanent ballooning of the aortic artery.
Pharmacological and genetic studies have pointed to multiple proteins, including …

Association of Genetic Polymorphisms and Serum Levels of miR-1-3p with Postoperative Mortality following Abdominal Aortic Aneurysm Repair

T Li, B Jiang, Y Wu, J Yang, C Ma, Y Yuan - Journal of Clinical Medicine, 2023 - mdpi.com
Background: Several miRNAs have been implicated in the clinical outcomes of
cardiovascular disorders, but the role of miR-1-3p in abdominal aortic aneurysm (AAA) …

Chemokine Receptor 2 Is A Theranostic Biomarker for Abdominal Aortic Aneurysms

Y Liu, SB Elizondo, S Sastriques-Dunlop, L Detering… - medRxiv, 2023 - medrxiv.org
Abdominal aortic aneurysm (AAA) is a degenerative vascular disease impacting aging
populations with a high mortality upon rupture. There are no effective medical therapies to …

[PDF][PDF] A REVIEW OF ABDOMINAL AORTIC ANEURYSMS: RISK FACTORS, SCREENING, PHARMACOLOGICAL APPROACH.

DA BRIE, A JIANU, R POPESCU, T MARCOVICI… - …, 2024 - farmaciajournal.com
Most patients with abdominal aortic aneurysm (AAA) are asymptomatic, being diagnosed
during an imaging evaluation for other symptoms. AAA rupture is an emergency, being one …

Exploring Preclinical Targets in Abdominal Aortic Aneurysm

A Balboa Ramilo - 2024 - diva-portal.org
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine
2058. 65 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-513-2154-7. Abdominal …

Investigating the Role of Epidermal Growth Factor Receptor in Abdominal Aortic Aneurysms

S Dayal - 2024 - search.proquest.com
The inability of adult vascular smooth muscle cells (SMCs) to facilitate elastic matrix
regeneration and repair renders it extremely difficult to reverse the pathophysiology of …