Signal transduction pathways linking polyamines to apoptosis
C Pignatti, B Tantini, C Stefanelli, F Flamigni - Amino acids, 2004 - Springer
Polyamines are important multifunctional cellular components and are classically
considered as mediators of cell growth and division. Recently polyamines have been also …
considered as mediators of cell growth and division. Recently polyamines have been also …
Protein kinase d regulates cell death pathways in experimental pancreatitis
J Yuan, Y Liu, T Tan, S Guha, I Gukovsky… - Frontiers in …, 2012 - frontiersin.org
Inflammation and acinar cell necrosis are two major pathological responses of acute
pancreatitis, a serious disorder with no current therapies directed to its molecular …
pancreatitis, a serious disorder with no current therapies directed to its molecular …
Bile salts induce resistance to apoptosis through NF-κB-mediated XIAP expression
DJ Turner, SM Alaish, T Zou, JN Rao, JY Wang… - Annals of …, 2007 - journals.lww.com
Apoptosis plays a critical role in intestinal mucosal homeostasis. We previously showed that
the bile salt taurodeoxycholate has a beneficial effect on the intestinal mucosa through an …
the bile salt taurodeoxycholate has a beneficial effect on the intestinal mucosa through an …
Polyamines regulate the stability of activating transcription factor-2 mRNA through RNA-binding protein HuR in intestinal epithelial cells
L Xiao, JN Rao, T Zou, L Liu, BS Marasa… - Molecular biology of …, 2007 - Am Soc Cell Biol
Maintenance of intestinal mucosal epithelial integrity requires polyamines that modulate the
expression of various genes involved in cell proliferation and apoptosis. Recently …
expression of various genes involved in cell proliferation and apoptosis. Recently …
[HTML][HTML] Exogenous spermidine alleviates Diabetic Myocardial Fibrosis Via suppressing inflammation and Pyroptosis in db/db mice
C Wei, J Xu, Y Liu, J Qadir, S Zhang… - Balkan Medical …, 2023 - ncbi.nlm.nih.gov
Background: The main pathological feature of diabetic cardiomyopathy (DCM) caused by
diabetes mellitus is myocardial fibrosis. According to recent studies in cardiology, it has …
diabetes mellitus is myocardial fibrosis. According to recent studies in cardiology, it has …
Tumor Necrosis Factor α Induces Spermidine/Spermine N1-Acetyltransferase through Nuclear Factor κBin Non-small Cell Lung Cancer Cells
N Babbar, A Hacker, Y Huang, RA Casero - Journal of Biological Chemistry, 2006 - ASBMB
Tumor necrosis factor α (TNFα) is a potent pleiotropic cytokine produced by many cells in
response to inflammatory stress. The molecular mechanisms responsible for the multiple …
response to inflammatory stress. The molecular mechanisms responsible for the multiple …
Gossypol suppresses NF-κB activity and NF-κB-related gene expression in human leukemia U937 cells
DO Moon, MO Kim, JD Lee, GY Kim - Cancer letters, 2008 - Elsevier
Recent studies indicate that gossypol possesses potent antitumor activities in vitro and in
vivo. The nuclear factor-kappa B (NF-κB) plays an important role in tumor cell growth …
vivo. The nuclear factor-kappa B (NF-κB) plays an important role in tumor cell growth …
Association of cooking oil fumes exposure with lung cancer: involvement of inhibitor of apoptosis proteins in cell survival and proliferation in vitro
HS Hung, WJ Wu, YW Cheng, TC Wu, KL Chang… - … /Genetic Toxicology and …, 2007 - Elsevier
Cooking oil fumes (COF) have been shown to be associated with lung cancer incidence in
Chinese women. Our recent report indicates that inhibitor of apoptosis protein 2 (IAP2) …
Chinese women. Our recent report indicates that inhibitor of apoptosis protein 2 (IAP2) …
[HTML][HTML] Rab27A overexpression promotes bladder cancer proliferation and chemoresistance through regulation of NF-κB signaling
J Liu, X Gong, X Zhu, D Xue, Y Liu, P Wang - Oncotarget, 2017 - ncbi.nlm.nih.gov
Overexpression of Rab27A has been found in human cancers. However, the clinical
significance and biological effects of Rab27A in bladder cancer tissues and cell lines have …
significance and biological effects of Rab27A in bladder cancer tissues and cell lines have …
Metabolic correlations of glucocorticoids and polyamines in inflammation and apoptosis
G Bjelaković, I Stojanović, T Jevtović Stoimenov… - Amino Acids, 2010 - Springer
Glucocorticoid hormones (GC) are essential in all aspects of human health and disease.
Their anti-inflammatory and immunosuppressive properties are reasons for therapeutic …
Their anti-inflammatory and immunosuppressive properties are reasons for therapeutic …