Jnk2 deletion disrupts intestinal mucosal homeostasis and maturation by differentially modulating RNA-binding proteins HuR and CUGBP1

HK Chung, JN Rao, T Zou, L Liu… - … of Physiology-Cell …, 2014 - journals.physiology.org
Homeostasis and maturation of the mammalian intestinal epithelium are preserved through
strict regulation of cell proliferation, apoptosis, and differentiation, but the exact mechanism …

蜈蚣提取液体外抗肝癌Bel-7404 细胞作用机制的研究

刘细平, 陈宏伟, 钟德玝, 周伦祥, 王劲 - 中国医师杂志, 2009 - cqvip.com
目的研究蜈蚣提取液(ECP) 对肝癌Bel-7404 细胞株的作用机制. 方法采用不同浓度ECP
作用于体外培养的肝癌细胞Bel-7404, 流式细胞仪检测治疗组与对照组的细胞周期及其凋亡率; …

多胺调控细胞生长机制的研究进展

张军, 韩钰, 王艳林 - 生命科学, 2014 - cqvip.com
多胺(腐胺, 精脒, 精胺) 是真核细胞体内重要的多聚阳离子, 对细胞的生长增殖发挥重要作用.
快速生长的细胞内含有高浓度的多胺, 降低多胺含量将抑制细胞的生长, 阻滞细胞周期 …

Apoptotic pathways and their regulation

G Brouckaert, M Kalai, X Saelens… - Apoptotic pathways as …, 2005 - Springer
Many studies have led to the identification of molecules involved in the signaling to cell
death and especially to apoptosis. This cell death program is characterized by distinct …

Apoptosis in the gastrointestinal tract

LR Johnson - Physiology of the gastrointestinal tract, 2006 - books.google.com
Cell death is a common event in multicellular organisms and is responsible for tissue
modeling during embryonic development, as well as homeostasis of cell number in various …

硼替佐米对K562 细胞增殖, 凋亡及其对XIAP 表达的影响

邵明, 孙玲, 崔雪艳, 韩雪飞, 陈胜梅, 王芳张, 红凌芝 - 中华血液学杂志, 2011 - cqvip.com
目的研究蛋白酶体抑制剂硼替佐米(bortezomi) 对白血病细胞株K562 细胞的增殖, 凋亡及X
连锁凋亡抑制蛋白(XIAP) 表达的影响. 方法将不同浓度的硼替佐米作用于K562 细胞, 采用WST …

X 连锁的凋亡抑制蛋白研究进展

韩岱, 霍霞, 李燕 - 癌变. 畸变. 突变, 2007 - cqvip.com
IAP (inhibitor of apoptosis) 是内源性凋亡抑制蛋白家族, 其中效力最强的是X
连锁凋亡抑制蛋白(X chromosome linked inhibitor of apoptosis protein, XIAP). 它主要通过BIR …

[HTML][HTML] Autonomous inhibition of apoptosis correlates with responsiveness of colon carcinoma cell lines to ciglitazone

DM Baron, U Kaindl, VJ Haudek-Prinz, E Bayer… - Plos one, 2014 - journals.plos.org
Colorectal cancer is a leading cause of mortality worldwide. Resistance to therapy is
common and often results in patients succumbing to the disease. The mechanisms of …

重组XIAP 对H2O2 诱导小肠上皮细胞凋亡的保护作用

张娴, 黄羽, 曾星 - 中国组织工程研究, 2012 - cjter.com
背景: XIAP 在细胞抗凋亡中发挥关键作用, 能作为与凋亡相关的多种疾病预防治疗的靶点. 目的:
构建大鼠重组XIAP 表达质粒, 观察其对H 2 O 2 诱导细胞凋亡的保护作用和机制. 方法: 采用RT …

Signaling through interleukin-1 type 1 receptor diminishes Haemophilus somnus lipooligosaccharide-mediated apoptosis of endothelial cells

MJ Sylte, CJ Kuckleburg, D Atapattu, FP Leite… - Microbial …, 2005 - Elsevier
During sepsis, endothelial cells are both a source and target of pro-inflammatory cytokines
(eg IL-1α, IL-1β, TNFα and others), which may be detrimental to vascular homeostasis. Our …