Punicalagin's protective effects on Parkinson's progression in socially isolated and socialized rats: insights into multifaceted pathway

HA Salem, K Abu-Elfotuh, S Alzahrani, NI Rizk, HS Ali… - Pharmaceutics, 2023 - mdpi.com
Parkinson's disease (PD) is a gradual deterioration of dopaminergic neurons, leading to
motor impairments. Social isolation (SI), a recognized stressor, has recently gained attention …

Crystallin mu in medial amygdala mediates the effect of social experience on cocaine seeking in males but not in females

DM Walker, X Zhou, AM Cunningham… - Biological …, 2022 - Elsevier
Background Social experiences influence susceptibility to substance use disorder. The
adolescent period is associated with the development of social reward and is exceptionally …

Prenatal maternal antibiotics treatment alters the gut microbiota and immune function of post-weaned prepubescent offspring

AM Madany, HK Hughes, P Ashwood - International journal of molecular …, 2022 - mdpi.com
This study aimed to investigate the immediate and continual perturbation to the gut
microbiota of offspring in the weeks post-weaning and how these may be modulated by …

[HTML][HTML] Youth team sports participation associates with reduced dimensional psychopathology through interaction with biological risk factors

K Kunitoki, D Hughes, S Elyounssi… - … psychiatry global open …, 2023 - Elsevier
Background Physical activity is associated with mental health benefits in youth. Here, we
used causal inference and triangulation with 2 levels of biology to substantiate relationships …

[HTML][HTML] Post-weaning social isolation increases the incentive value of nicotine-related contexts and decreases the accumulation of ΔFosB in nucleus accumbens in …

DM Cortés-Patiño, H Ballesteros-Acosta… - Pharmacology …, 2023 - Elsevier
Adolescent social conditions profoundly affect vulnerability to drug abuse. Preclinical studies
have shown that preventing social interactions during adolescence increases the rewarding …

Post-weaning social isolation in male and female prairie voles: impacts on central and peripheral immune system

ML Donovan, EK Chun, Y Liu, Z Wang - Frontiers in behavioral …, 2022 - frontiersin.org
The socially monogamous prairie vole (Microtus ochrogaster) offers a unique opportunity to
examine the impacts of adolescent social isolation on the brain, immune system, and …

[HTML][HTML] Нейробиологические основы формирования поведения и употребления подростками психоактивных веществ (обзор литературы)

ЕВ Булычева - Гигиена и санитария, 2022 - cyberleninka.ru
Введение. Подростковый возраст является критическим периодом в онтогенезе.
Сложное и гетерохронное созревание различных структур головного мозга под …

[HTML][HTML] Age-related impact of social isolation in mice: Young vs middle-aged

DM Magalhães, M Mampay, AM Sebastião… - Neurochemistry …, 2024 - Elsevier
Social isolation is a chronic mild stressor and a significant risk factor for mental health
disorders. Herein we explored the impact of social isolation on depression-and anxiety-like …

Age-dependent effects of social isolation on mesolimbic dopamine release

MA McWain, RL Pace, PA Nalan, DB Lester - Experimental Brain Research, 2022 - Springer
In humans, social isolation is a known risk factor for disorders such as substance use
disorder and depression. In rodents, social isolation is a commonly used environmental …

The dorsal raphe-to-ventral hippocampal projection modulates reactive aggression through 5HT1B receptors

PY Chien, CL Su, PH Liu, CH Chang… - European Journal of …, 2024 - Elsevier
Maladaptive impulsive aggression is a core symptom of neuropsychiatric disorders such as
schizophrenia. While uncontrolled impulsive aggression dampens societal safety, there is a …