Head and neck cancer

A Argiris, MV Karamouzis, D Raben, RL Ferris - The Lancet, 2008 - thelancet.com
Most head and neck cancers are squamous cell carcinomas that develop in the upper
aerodigestive epithelium after exposure to carcinogens such as tobacco and alcohol …

Human papillomavirus: gene expression, regulation and prospects for novel diagnostic methods and antiviral therapies

SV Graham - Future microbiology, 2010 - Taylor & Francis
Human papillomaviruses (HPVs) cause diseases ranging from benign warts to invasive
tumors. A subset of these viruses termed 'high risk 'infect the cervix where persistent …

The role of HPV RNA transcription, immune response‐related gene expression and disruptive TP53 mutations in diagnostic and prognostic profiling of head and neck …

G Wichmann, M Rosolowski, K Krohn… - … journal of cancer, 2015 - Wiley Online Library
Stratification of head and neck squamous cell carcinomas (HNSCC) based on HPV16 DNA
and RNA status, gene expression patterns, and mutated candidate genes may facilitate …

Regulation of human papillomavirus gene expression by splicing and polyadenylation

C Johansson, S Schwartz - Nature reviews Microbiology, 2013 - nature.com
Human papillomaviruses (HPVs) are small DNA tumour viruses that are present in more
than 99% of all cervical cancers. The ability of these viruses to cause disease is partly …

Biology of human papillomavirus infections in head and neck carcinogenesis

J Rautava, S Syrjänen - Head and neck pathology, 2012 - Springer
The association between human papillomaviruses (HPV) and oral cancer was initially
suggested nearly 30 years ago by us. Today, the research interest of head and neck …

[HTML][HTML] Analysis of The Cancer Genome Atlas sequencing data reveals novel properties of the human papillomavirus 16 genome in head and neck squamous cell …

TJ Nulton, AL Olex, M Dozmorov, IM Morgan… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Human papillomavirus (HPV) DNA is detected in up to 80% of oropharyngeal carcinomas
(OPC) and this HPV positive disease has reached epidemic proportions. To increase our …

Productive lifecycle of human papillomaviruses that depends upon squamous epithelial differentiation

N Kajitani, A Satsuka, A Kawate, H Sakai - Frontiers in microbiology, 2012 - frontiersin.org
Human papillomaviruses (HPVs) target the stratified epidermis, and can causes diseases
ranging from benign condylomas to malignant tumors. Infections of HPVs in the genital tract …

[HTML][HTML] Oxidative stress in female cancers

GM Calaf, U Urzua, L Termini, F Aguayo - Oncotarget, 2018 - ncbi.nlm.nih.gov
Breast, cervical and ovarian cancers are highly prevalent in women worldwide.
Environmental, hormonal and viral-related factors are especially relevant in the …

Differential methylation of E2 binding sites in episomal and integrated HPV 16 genomes in preinvasive and invasive cervical lesions

A Chaiwongkot, S Vinokurova… - … journal of cancer, 2013 - Wiley Online Library
Enhanced expression of the HPV 16 E6‐E7 oncogenes may trigger neoplastic
transformation of the squamous epithelial cells at the uterine cervix. The HPV E2 protein is a …

Methylation of human papillomavirus type 16 genome and risk of cervical precancer in a Costa Rican population

L Mirabello, C Sun, A Ghosh… - Journal of the …, 2012 - academic.oup.com
Background Previous studies have suggested an association between human
papillomavirus type 16 (HPV16) genome methylation and cervical intraepithelial neoplasia …