In spite of the considerable achievements in the field of regenerative medicine in the past
several decades, osteochondral defect regeneration remains a challenging issue among …

Hydrogel microparticles (HMPs) are promising for biomedical applications, ranging from the
therapeutic delivery of cells and drugs to the production of scaffolds for tissue repair and …

Transplantation of synovial fluid-derived mesenchymal stem cells (SF-MSCs) is a viable
therapy for cartilage degeneration of osteoarthritis (OA). But controlling chondrogenic …

Osteochondral defect repair in osteoarthritis (OA) remains an unsolved clinical problem due
to the lack of enough seed cells in the defect and chronic inflammation in the joint. To …

Joint diseases are one of the most common causes of morbidity and disability worldwide.
The main diseases that affect joint cartilage are osteoarthritis and rheumatoid arthritis, which …

The early stages of progressive degeneration of cartilage in articular joints are a hallmark of
osteoarthritis. Healthy cartilage is lubricated by brush-like cartilage-binding nanofibres with …

The encapsulation of drugs inside polymeric nanoparticles/microparticles is a strategy
currently employed in the search for new and more effective therapies. The use of …

Osteoarthritis (OA) is a progressive chronic inflammation that leads to cartilage
degeneration. OA Patients are commonly given pharmacological treatment, but the available …

Osteoarthritis (OA) is a highly prevalent whole-joint disease that causes disability and pain
and affects a patient's quality of life. However, currently, there is a lack of effective early …

Hydrogels have been widely used as the carrier material of therapeutic cell and drugs for
articular cartilage repair. We previously demonstrated a unique host-guest macromer (HGM) …