Over the past 15 years, sequencing of the human genome and The Cancer Genome Atlas
(TCGA) project have led to comprehensive lists of single-nucleotide polymorphisms (SNPs) …

The decline of oxygen tension in the tissues below the physiological demand leads to the
hypoxic adaptive response. This physiological consequence enables cells to recover from …

With the first RNA interference (RNAi) drug (ONPATTRO (patisiran)) on the market, we
witness the RNAi therapy field reaching a critical turning point, when further improvements in …

Schizophrenia is a chronic, heterogeneous neurodevelopmental disorder that has complex
symptoms and uncertain etiology. Mounting evidence indicates the involvement of genetics …

Pathogenic bacteria cause various infections worldwide, especially in immunocompromised
and other susceptible individuals, and are also associated with high infant mortality rates in …

Cold viruses have generally been considered fairly innocuous until the appearance of the
severe acute respiratory coronavirus 2 (SARS-CoV-2) in 2019, which caused the …

Abstract Severe Acute Respiratory Syndrome Coronavirus‐2 (SARS‐CoV‐2) is the novel
coronavirus responsible for worldwide coronavirus disease (COVID‐19). We previously …

The complementary interaction of microRNAs (miRNAs) with their binding sites in the 3′
untranslated regions (3′ UTRs) of target gene mRNAs represses translation, playing a …

Single nucleotide variants (SNVs) contribute to human genomic diversity. Synonymous
SNVs are previously considered to be “silent,” but mounting evidence has revealed that …

Abstract microRNAs (miRNAs) are nowadays recognized as an essential component of
gene regulatory networks. Furthermore, deregulation of miRNAs expression often …