Asymmetric desymmetrization of allylic oxidation of 4, 5-epoxycyclohex-1-ene (1) took place
in the presence of 2.5 mol% of Cu (CH3CN) 4PF6 and 3 mol% of chiral N, N-bidentate …

Cationic lipids are currently actively investigated as an alternative approach to recombinant
viruses for gene transfer studies and gene therapy applications. Basically, they rely on the …

Electron paramagnetic resonance (EPR) spectroscopy was utilized to investigate the
correlation between RNA structure and RNA internal dynamics in complexes of HIV-1 TAR …

Guanidinylated neomycin (GNeo) can transport bioactive, high molecular weight cargo into
the interior of cells in a process that depends on cell surface heparan sulfate proteoglycans …

The binding of paromomycin and similar antibiotics to the small (30S) ribosomal subunit has
been studied using continuum electrostatics methods. Crystallographic information from a …

Though l‐arginine‐containing polymers show versatile biological functions, a precisely
controlled synthesis of poly (ethylene glycol)‐b‐poly (l‐arginine)(PEG‐b‐PArg) block …

Heteroduplex oligonucleotides (HDOs), composed of a DNA/LNA gapmer and its
complementary RNA, are a novel, promising candidates for antisense drugs. We previously …

Herein, we report the identification of RNA hairpin loops that bind derivatives of kanamycin
A, tobramycin, neamine, and neomycin B via two-dimensional combinatorial screening, a …

The design and synthesis of two Janus-type heterocycles with the capacity to simultaneously
recognize guanine and uracyl in GU mismatched pairs through complementary hydrogen …

Abstract Ribonuclease P (RNase P) is a Mg 2+-dependent endoribonuclease responsible
for the 5′-maturation of transfer RNAs. It is a ribonucleoprotein complex containing an …