[HTML][HTML] Computational identification of potential inhibitors targeting cdk1 in colorectal cancer

UC Ogbodo, OA Enejoh, CH Okonkwo… - Frontiers in …, 2023 - ncbi.nlm.nih.gov
Introduction: Despite improved treatment options, colorectal cancer (CRC) remains a huge
public health concern with a significant impact on affected individuals. Cell cycle …

Thioredoxin Domain Containing 5 (TXNDC5): Friend or Foe?

SH Bidooki, MA Navarro, SCM Fernandes… - Current Issues in …, 2024 - mdpi.com
This review focuses on the thioredoxin domain containing 5 (TXNDC5), also known as
endoplasmic reticulum protein 46 (ERp46), a member of the protein disulfide isomerase …

Differential expression analysis of miRNAs and mRNAs in epilepsy uncovers potential biomarkers

FE Abed, G Baraket, MN Nyamari, C Naitore, OI Awe - bioRxiv, 2023 - biorxiv.org
Epilepsy is a neurological disease defined by episodes of synchronous convulsions.
Recently, miRNAs have been proven as promising biomarkers for multiple ailments like …

Expression level analysis of ACE2 receptor gene in african-American and non-african-American COVID-19 patients

MN Nyamari, KM Omar, AF Fayehun, O Dachi… - bioRxiv, 2023 - biorxiv.org
Background: The COVID-19 pandemic caused by SARS-CoV-2 has spread rapidly across
the continents. While the incidence of COVID-19 has been reported to be higher among …

Investigating antimicrobial resistance genes in Kenya, Uganda and Tanzania cattle using metagenomics

KM Omar, GL Kitundu, AO Jimoh, DN Namikelwa… - PeerJ, 2024 - peerj.com
Antimicrobial resistance (AMR) is a growing problem in African cattle production systems,
posing a threat to human and animal health and the associated economic value chain …

Adaptive best subset selection algorithm and genetic algorithm aided ensemble learning method identified a robust severity score of COVID‐19 patients

W Kong, J Zhu, S Bi, L Huang, P Wu, SJ Zhu - iMeta, 2023 - Wiley Online Library
Currently, since there are still some inconsistencies in the severity data types of COVID‐19
among different hospitals or sources [8], we aimed to establish a consistent severity score for …