Impact of DNA polymorphisms in key DNA base excision repair proteins on cancer risk
B Karahalil, VA Bohr… - Human & experimental …, 2012 - journals.sagepub.com
Genetic variation in DNA repair genes can modulate DNA repair capacity and may be
related to cancer risk. However, study findings have been inconsistent. Inheritance of variant …
related to cancer risk. However, study findings have been inconsistent. Inheritance of variant …
PARP inhibitors in head and neck cancer: Molecular mechanisms, preclinical and clinical data
Abstract Poly (ADP-ribose) polymerase (PARP) inhibitors (PARPi) have revolutionized the
treatment landscape in several cancers. PARPi increase DNA damage particularly in tumors …
treatment landscape in several cancers. PARPi increase DNA damage particularly in tumors …
Altered expression of circadian clock genes in head and neck squamous cell carcinoma
Head and neck squamous cell carcinoma (HNSCC) means a group of cancers developed
from the upper aerodigestive tract, and 90% of them are squamous cell carcinomas. HNSCC …
from the upper aerodigestive tract, and 90% of them are squamous cell carcinomas. HNSCC …
Molecular biology of head and neck cancer: risks and pathways
Patients present with a differential baseline risk of cancer based on normal and expected
variations in genes associated with cancer. The baseline risk of developing cancer is acted …
variations in genes associated with cancer. The baseline risk of developing cancer is acted …
Molecular techniques and genetic alterations in head and neck cancer
PK Ha, SS Chang, CA Glazer, JA Califano, D Sidransky - Oral oncology, 2009 - Elsevier
It is well known that cellular DNA alterations can lead to the formation of cancer, and there
has been much discovery in the pathways involved in the development of head and neck …
has been much discovery in the pathways involved in the development of head and neck …
Association of Single Nucleotide Polymorphisms in SOD2, XRCC1 and XRCC3 with Susceptibility for the Development of Adverse Effects Resulting from …
RJ Burri, RG Stock, JA Cesaretti… - Radiation …, 2008 - meridian.allenpress.com
Abstract Burri, RJ, Stock, RG, Cesaretti, JA, Atencio, DP, Peters, S., Peters, CA, Fan, G.,
Stone, NN, Ostrer, H. and Rosenstein, BS Association of Single Nucleotide Polymorphisms …
Stone, NN, Ostrer, H. and Rosenstein, BS Association of Single Nucleotide Polymorphisms …
Functional polymorphisms of base excision repair genes XRCC1 and APEX1 predict risk of radiation pneumonitis in patients with non–small cell lung cancer treated …
M Yin, Z Liao, Z Liu, LE Wang, D Gomez… - International Journal of …, 2011 - Elsevier
PURPOSE: To explore whether functional single nucleotide polymorphisms (SNPs) of base-
excision repair genes are predictors of radiation treatment-related pneumonitis (RP), we …
excision repair genes are predictors of radiation treatment-related pneumonitis (RP), we …
Association between DNA repair gene polymorphisms and risk of glioma: a systematic review and meta-analysis
M Adel Fahmideh, J Schwartzbaum… - Neuro …, 2014 - academic.oup.com
Background Association studies of germline DNA repair single nucleotide polymorphisms
(SNPs) and glioma risk have yielded inconclusive results. We therefore performed a …
(SNPs) and glioma risk have yielded inconclusive results. We therefore performed a …
Analysis of oxidative DNA damage and its repair in Polish patients with diabetes mellitus type 2: Role in pathogenesis of diabetic neuropathy
A Merecz, L Markiewicz, A Sliwinska… - Advances in medical …, 2015 - Elsevier
Purpose Distal symmetric polyneuropathy (DSPN) is common complication of type 2
diabetes (T2DM). In this work we investigated the role of oxidative damage in connection …
diabetes (T2DM). In this work we investigated the role of oxidative damage in connection …
Oxidative stress-induced CREB upregulation promotes DNA damage repair prior to neuronal cell death protection
N Pregi, LM Belluscio, BG Berardino… - Molecular and cellular …, 2017 - Springer
Abstract cAMP response element-binding (CREB) protein is a cellular transcription factor
that mediates responses to different physiological and pathological signals. Using a model …
that mediates responses to different physiological and pathological signals. Using a model …