Senescence is a cellular aging process in all multicellular organisms. It is characterized by a
decay in cellular functions and proliferation, resulting in increased cellular damage and …

Diseases of the heart and the kidney, including heart failure and chronic kidney disease, can
dramatically impair life expectancy and the quality of life of patients. The heart and kidney …

Ferroptosis is a cell death mode of lipid peroxidation caused by iron metabolism disorder
and redox imbalance, which is closely associated with the evolution of tumour and ischemia …

There is new and increasing evidence from in vitro, in vivo and clinical studies implicating
the pivotal role of iron and associated metabolic pathways in the initiation, progression and …

Iron is essential for all organisms and cells. Diseases of iron imbalance affect billions of
patients, including those with iron overload and other forms of iron toxicity. Excess iron load …

Ferroptosis is a form of cell death that is distinguished from other types of death for its
peculiar characteristics of death regulated by iron accumulation, increase in ROS, and lipid …

Ferroptosis, a regulated form of cellular death characterized by the iron-mediated
accumulation of lipid peroxides, provides a novel avenue for delving into the intersection of …

Selenium is an essential trace element that is essential for various metabolic processes,
protection from oxidative stress and proper functioning of the cardiovascular system. Se …

Cardiovascular diseases (CVDs), encompassing ischaemic heart disease, cardiomyopathy,
and heart failure, among others, are the most prevalent complications of diabetes and the …

Schizandrin B (SchB) protects against oxidative, inflammatory, and ferroptotic injury.
Oxidative stress and inflammation are indispensably involved in nephrolithiasis and …