Septins are an integral component of the cytoskeleton, assembling into higher-order
oligomers and filamentous polymers that associate with actin filaments, microtubules and …

Septins are conserved guanine nucleotide-binding proteins that polymerize into filaments at
the cell cortex or in association with other cytoskeletal proteins, such as actin or …

In order to fully understand any complex biochemical system from a mechanistic point of
view, it is necessary to have access to the three-dimensional structures of the molecular …

Electrostatic intermolecular interactions are important in many aspects of biology. We have
studied the main electrostatic features involved in the interaction of the receptor-binding …

Septin GTPases form nonpolar heteropolymers that play important roles in cytokinesis and
other cellular processes. The ability to form heteropolymers appears to be critical to many …

Septins are cytoskeletal proteins that assemble into hetero-oligomeric complexes and sense
micron-scale membrane curvature. During infection with Shigella flexneri, an invasive …

A new betacoronavirus named SARS-CoV-2 has emerged as a new threat to global health
and economy. A promising target for both diagnosis and therapeutics treatments of the new …

Septins are conserved cytoskeletal proteins that regulate cell cortex mechanics. The
mechanisms of their interactions with the plasma membrane remain poorly understood …

Septins are cytoskeletal proteins conserved from algae and protists to mammals. A unique
feature of septins is their presence as heteromeric complexes that polymerize into filaments …

In order to form functional filaments, human septins must assemble into hetero-oligomeric
rod-like particles which polymerize end-to-end. The rules governing the assembly of these …