The endoplasmic reticulum (ER) functions as a quality-control organelle for protein
homeostasis, or “proteostasis”. The protein quality control systems involve ER-associated …

The pre-Descemet's layer/Dua's layer, also termed the Dua-Fine layer and the pre-posterior
limiting lamina layer, lies anterior to the Descemet's membrane in the cornea, is 10 μm …

Corneal dystrophies are broadly defined as inherited disorders that affect any layer of the
cornea and are usually progressive, bilateral conditions that do not have systemic effects …

Macular corneal dystrophy (MCD) is ascribed to mutations in the carbohydrate
sulfotransferase (CHST6) gene affecting keratan sulfate (KS) hydrophilicity and causing non …

The eye is a complex sensory organ that enables visual perception of the world. The
dysfunction of any of these tissues can impair vision. Conduction studies on laboratory …

The aim of the study was to investigate oxidative stress as well as cellular protein
accumulation in corneal diseases including keratoconus (KC), macular corneal dystrophy …

Matrix metalloproteinases (MMPs) are endopeptidases that are responsible for the
degradation of several components of the extracellular matrix (ECM) and some non-ECM …

Corneal dystrophies are a group of non-inflammatory inherited disorders of the cornea. This
review considers treatment options for epithelial-stromal and stromal corneal dystrophies …

Autophagy is a catabolic self-degradative pathway that promotes the degradation and
recycling of intracellular material through the lysosomal compartment. Although first believed …

Axons from deep heterotopia do not extend through U-fibers, except transmantle dysplasias.
Keratan sulfate (KS) in fetal spinal cord/brainstem median septum selectively repels …