Pertussis is a severe respiratory infection caused by Bordetella pertussis, and in 2008,
pertussis was associated with an estimated 16 million cases and 195,000 deaths globally …

BACKGROUND AND OBJECTIVES: Pertussis incidence is increasing, possibly due to the
introduction of acellular vaccines, which may have decreased the durability of immune …

This report compiles and summarizes all recommendations from CDC's Advisory Committee
on Immunization Practices (ACIP) regarding prevention and control of tetanus, diphtheria …

Methods In monthly teleconferences during 2012, the ACIP Pertussis Vaccines Work Group
considered published, peer-reviewed literature and unpublished data relevant to …

Background Two Tdap vaccines are licensed for use in the United States. Boostrix
(GlaxoSmithKline) is approved for a single dose in persons aged≥ 10 years; Adacel (Sanofi …

Pregnancy and the postpartum period are associated with elevated risks to both mother and
infant from infectious disease. Vaccination of pregnant women, also called maternal …

The Global Pertussis Initiative (GPI) is an expert scientific forum addressing the worldwide
burden of pertussis, which remains a serious health issue, especially in infants. This age …

Recent reemergence of pertussis (whooping cough) in highly vaccinated populations and
rapid expansion of Bordetella pertussis strains lacking pertactin (PRN), a common acellular …

Background: A resurgence of pertussis cases among both vaccinated and unvaccinated
people raises questions about vaccine effectiveness over time. Our objective was to study …

This module is part of the WHO series The immunological basis for immunization, which was
initially developed in 1993 as a set of eight modules, comprising one module on general …