Effectiveness and safety of atezolizumab-bevacizumab in patients with unresectable hepatocellular carcinoma: a systematic review and meta-analysis

AV Kulkarni, H Tevethia, K Kumar, M Premkumar… - …, 2023 - thelancet.com
Background Atezolizumab-bevacizumab (atezo-bev) is recommended as first-line therapy
for patients with unresectable hepatocellular carcinoma (uHCC). However, its effectiveness …

Biomarkers for immunotherapy of hepatocellular carcinoma

TF Greten, A Villanueva, F Korangy, B Ruf… - Nature Reviews …, 2023 - nature.com
Immune-checkpoint inhibitors (ICIs) are now widely used for the treatment of patients with
advanced-stage hepatocellular carcinoma (HCC). Two different ICI-containing regimens …

[HTML][HTML] Blood biomarkers predict outcomes in patients with hepatocellular carcinoma treated with immune checkpoint Inhibitors: A pooled analysis of 44 retrospective …

L Zhang, J Feng, T Kuang, D Chai, Z Qiu… - International …, 2023 - Elsevier
Objective We conducted the first meta-analysis to identify the predictive significance of
baseline blood biomarkers (such as neutrophil to lymphocyte ratio (NLR), early alpha …

Non-invasive biomarkers for immunotherapy in patients with hepatocellular carcinoma: current knowledge and future perspectives

M Pallozzi, N Di Tommaso, V Maccauro, F Santopaolo… - Cancers, 2022 - mdpi.com
Simple Summary The search for non-invasive biomarkers is a hot topic in modern oncology,
since a tissue biopsy has significant limitations in terms of cost and invasiveness. The …

Predicting outcomes of atezolizumab and bevacizumab treatment in patients with hepatocellular carcinoma

JW Han, JW Jang - International Journal of Molecular Sciences, 2023 - mdpi.com
A combination of atezolizumab with bevacizumab (AB) is the first regimen that has shown
superiority compared to sorafenib and is now being used as the systemic treatment of choice …

Efficacy and safety of atezolizumab plus bevacizumab treatment for advanced hepatocellular carcinoma in the real world: a single-arm meta-analysis

X Gao, R Zhao, H Ma, S Zuo - BMC cancer, 2023 - Springer
Background Atezolizumab plus bevacizumab was approved in 2020 as a first-line treatment
for advanced hepatocellular carcinoma (HCC). The purpose of this study was to assess the …

2023 update of Indian national association for study of the liver consensus on management of intermediate and advanced hepatocellular carcinoma: the Puri III …

A Kumar, SK Acharya, SP Singh, A Duseja… - Journal of Clinical and …, 2024 - Elsevier
Hepatocellular carcinoma (HCC) presents significant treatment challenges despite
considerable advancements in its management. The Indian National Association for the …

Similar efficacy and safety between lenvatinib versus atezolizumab plus bevacizumab as the first‐line treatment for unresectable hepatocellular carcinoma

CW Su, W Teng, PT Lin, WJ Jeng, KA Chen… - Cancer …, 2023 - Wiley Online Library
Background Lenvatinib and atezolizumab plus bevacizumab (A+ B) have been used for
unresectable hepatocellular carcinoma (HCC) as first‐line therapy. Real‐world studies …

Biomarkers predicting the efficacy of immune checkpoint inhibitors in hepatocellular carcinoma

R Qin, T Jin, F Xu - Frontiers in Immunology, 2023 - frontiersin.org
In recent years, immune checkpoint inhibitors (ICIs) have emerged as a transformative
approach in treating advanced hepatocellular carcinoma (HCC). Despite their success …

Prognostic biomarkers associated with immune checkpoint inhibitors in hepatocellular carcinoma

X Chen, L Kou, X Xie, S Su, J Li, Y Li - Immunology, 2024 - Wiley Online Library
The treatment of hepatocellular carcinoma (HCC), particularly advanced HCC, has been a
serious challenge. Immune checkpoint inhibitors (ICIs) are landmark drugs in the field of …