Background: Previous evidence-based guidelines on the management of intra-abdominal
infection (IAI) were published by the Surgical Infection Society (SIS) in 1992, 2002, and …

Postoperative antibiotics are recommended after appendectomy for complex appendicitis to
reduce infectious complications. The duration of this treatment varies considerably between …

Background Acute appendicitis is the most common surgical emergency in children. Despite
this, there is no core outcome set (COS) described for randomised controlled trials (RCTs) in …

Background: This study evaluated the efficacy and safety of ertapenem versus a
combination of gentamicin plus metronidazole in pediatric patients with diffuse peritonitis …

Objective: To analyze the preoperative use of antibiotics in children and adolescents
requiring appendectomy. Data source: Integrative review was performed in the MEDLINE …

There is no global consensus on the conduct of clinical trials in children and neonates with
complicated clinical infection syndromes. No comprehensive regulatory guidance exists for …

Introduction Acute appendicitis is the most common emergency condition in pediatric
surgery. Historically, a triple-antibiotic therapy consisted of ampicillin, gentamicin, and …

Purpose Randomized controlled trials (RCT) in pediatric appendicitis remain limited, and the
robustness of available evidence is unknown. The aim of this study was to determine the …

Objective: Surgical site infections (SSIs), especially deep/organ-space SSIs, are common
and serious complications following appendectomy. This review aimed to explore the …

Background: Exploration of the risk factors of recurrent appendiceal abscess after initial non-
surgical treatment without drainage in children with appendiceal abscess. Patients and …