[HTML][HTML] Acetylcholine as a neuromodulator: cholinergic signaling shapes nervous system function and behavior

MR Picciotto, MJ Higley, YS Mineur - Neuron, 2012 - cell.com
Acetylcholine in the brain alters neuronal excitability, influences synaptic transmission,
induces synaptic plasticity, and coordinates firing of groups of neurons. As a result, it …

Serotonin modulation of cortical neurons and networks

P Celada, MV Puig, F Artigas - Frontiers in integrative neuroscience, 2013 - frontiersin.org
The serotonergic pathways originating in the dorsal and median raphe nuclei (DR and MnR,
respectively) are critically involved in cortical function. Serotonin (5-HT), acting on …

Reassessment of the structural basis of the ascending arousal system

P Fuller, D Sherman, NP Pedersen… - Journal of …, 2011 - Wiley Online Library
The “ascending reticular activating system” theory proposed that neurons in the upper
brainstem reticular formation projected to forebrain targets that promoted wakefulness. More …

Cognitive and perceptual functions of the visual thalamus

YB Saalmann, S Kastner - Neuron, 2011 - cell.com
The thalamus is classically viewed as passively relaying information to the cortex. However,
there is growing evidence that the thalamus actively regulates information transmission to …

Discharge profiles across the sleep–waking cycle of identified cholinergic, GABAergic, and glutamatergic neurons in the pontomesencephalic tegmentum of the rat

S Boucetta, Y Cissé, L Mainville, M Morales… - Journal of …, 2014 - Soc Neuroscience
Distributed within the laterodorsal tegmental and pedunculopontine tegmental nuclei (LDT
and PPT), cholinergic neurons in the pontomesencephalic tegmentum have long been …

A motor theory of sleep-wake control: arousal-action circuit

D Liu, Y Dan - Annual review of neuroscience, 2019 - annualreviews.org
Wakefulness, rapid eye movement (REM) sleep, and non–rapid eye movement (NREM)
sleep are characterized by distinct electroencephalogram (EEG), electromyogram (EMG) …

Circadian and wakefulness-sleep modulation of cognition in humans

KP Wright, CA Lowry, MK LeBourgeois - Frontiers in molecular …, 2012 - frontiersin.org
Cognitive and affective processes vary over the course of the 24 h day. Time of day
dependent changes in human cognition are modulated by an internal circadian timekeeping …

Prominent burst firing of dopaminergic neurons in the ventral tegmental area during paradoxical sleep

L Dahan, B Astier, N Vautrelle, N Urbain… - …, 2007 - nature.com
Dopamine is involved in motivation, memory, and reward processing. However, it is not clear
whether the activity of dopamine neurons is related or not to vigilance states. Using unit …

Neurobiological mechanisms for the regulation of mammalian sleep–wake behavior: reinterpretation of historical evidence and inclusion of contemporary cellular and …

S Datta, RR MacLean - Neuroscience & Biobehavioral Reviews, 2007 - Elsevier
At its most basic level, the function of mammalian sleep can be described as a restorative
process of the brain and body; recently, however, progressive research has revealed a host …

The neurobiological mechanisms and treatments of REM sleep disturbances in depression

YQ Wang, R Li, MQ Zhang, Z Zhang… - Current …, 2015 - ingentaconnect.com
Most depressed patients suffer from sleep abnormalities, which are one of the critical
symptoms of depression. They are robust risk factors for the initiation and development of …