[HTML][HTML] Evolving pathologic concepts of serrated lesions of the colorectum
JH Kim, GH Kang - Journal of pathology and translational medicine, 2020 - ncbi.nlm.nih.gov
Here, we provide an up-to-date review of the histopathology and molecular pathology of
serrated colorectal lesions. First, we introduce the updated contents of the 2019 World …
serrated colorectal lesions. First, we introduce the updated contents of the 2019 World …
Sessile serrated lesions: Clinicopathological characteristics, endoscopic diagnosis, and management
T Murakami, T Kurosawa, H Fukushima… - Digestive …, 2022 - Wiley Online Library
The 2019 World Health Organization (WHO) Classification of Tumours of the Digestive
System (5th edition) introduced the term “sessile serrated lesion”(SSL) to replace the term …
System (5th edition) introduced the term “sessile serrated lesion”(SSL) to replace the term …
Prognostic implications of CpG island hypermethylator phenotype in colorectal cancers
JH Kim, SH Shin, HJ Kwon, NY Cho, GH Kang - Virchows Archiv, 2009 - Springer
CpG island methylator phenotype (CIMP) refers to a subset of colorectal cancers (CRCs)
that are characterized by concordant hypermethylation of multiple CpG island loci. CIMP+ …
that are characterized by concordant hypermethylation of multiple CpG island loci. CIMP+ …
[HTML][HTML] A serrated colorectal cancer pathway predominates over the classic WNT pathway in patients with hyperplastic polyposis syndrome
KS Boparai, E Dekker, MM Polak, AR Musler… - The American journal of …, 2011 - Elsevier
Hyperplastic polyposis syndrome (HPS) is characterized by the presence of multiple
colorectal serrated polyps and is associated with an increased colorectal cancer (CRC) risk …
colorectal serrated polyps and is associated with an increased colorectal cancer (CRC) risk …
Beta-catenin nuclear labeling is a common feature of sessile serrated adenomas and correlates with early neoplastic progression after BRAF activation
S Yachida, S Mudali, SA Martin… - The American journal …, 2009 - journals.lww.com
Recent observations indicate that some sessile serrated adenomas (SSAs) have aberrant β-
catenin nuclear labeling, implicating the Wnt pathway in the molecular progression of SSAs …
catenin nuclear labeling, implicating the Wnt pathway in the molecular progression of SSAs …
Clinicopathological significance of PTEN loss and the phosphoinositide 3-kinase/Akt pathway in sporadic colorectal neoplasms: is PTEN loss predictor of local …
T Colakoglu, S Yildirim, F Kayaselcuk, TZ Nursal… - The American journal of …, 2008 - Elsevier
BACKGROUND: PTEN is a tumor-suppressor gene located on chromosome 10. Deficient
PTEN expression leads to activation of the phosphoinositide 3-kinase (PI3K)/Akt (pAkt) …
PTEN expression leads to activation of the phosphoinositide 3-kinase (PI3K)/Akt (pAkt) …
How the BRAF V600E Mutation Defines a Distinct Subgroup of Colorectal Cancer: Molecular and Clinical Implications
CE Bond, VLJ Whitehall - Gastroenterology research and …, 2018 - Wiley Online Library
The BRAF oncogene is an integral component of the MAP kinase pathway, and an activating
V600E mutation occurs in 15% of sporadic colorectal cancer. This is an early event in …
V600E mutation occurs in 15% of sporadic colorectal cancer. This is an early event in …
KRAS mutations in traditional serrated adenomas from Korea herald an aggressive phenotype
KM Kim, EJ Lee, YH Kim, DK Chang… - The American journal of …, 2010 - journals.lww.com
The pathogenesis and risk of malignancy of traditional serrated adenomas (TSAs) are
unclear. In North America, TSAs are relatively uncommon, occur mainly in the left colon, and …
unclear. In North America, TSAs are relatively uncommon, occur mainly in the left colon, and …
Systematic review of narrow-band imaging for the detection and differentiation of neoplastic and nonneoplastic lesions in the colon (with videos)
In the past decades, the perspective of diagnostic endoscopy has changed from diagnosing
evident disease to the detection of subtle abnormalities. Modern endoscopic practice …
evident disease to the detection of subtle abnormalities. Modern endoscopic practice …
[HTML][HTML] Endoscopic diagnosis of sessile serrated adenoma/polyp with and without dysplasia/carcinoma
T Murakami, N Sakamoto… - World Journal of …, 2018 - ncbi.nlm.nih.gov
Sessile serrated adenoma/polyps (SSA/Ps) are early precursor lesions in the serrated
neoplasia pathway, which results in colorectal carcinomas with BRAF mutations, methylation …
neoplasia pathway, which results in colorectal carcinomas with BRAF mutations, methylation …