Epidemiology and pathogenesis of ulcerative colitis

L Du, C Ha - Gastroenterology Clinics, 2020 - gastro.theclinics.com
Ulcerative colitis (UC) is a chronic immune-mediated inflammatory disorder of the colon
(IBD) that is hypothesized to be related to exposure to environmental risk factors leading to …

Inflammatory links between high fat diets and diseases

Y Duan, L Zeng, C Zheng, B Song, F Li… - Frontiers in …, 2018 - frontiersin.org
In recent years, chronic overnutrition, such as consumption of a high-fat diet (HFD), has
been increasingly viewed as a significant modifiable risk factor for diseases such as …

Association of ultra-processed food intake with risk of inflammatory bowel disease: prospective cohort study

N Narula, ECL Wong, M Dehghan, A Mente… - Bmj, 2021 - bmj.com
Objective To evaluate the relation between intake of ultra-processed food and risk of
inflammatory bowel disease (IBD). Design Prospective cohort study. Setting 21 low, middle …

A comprehensive review and update on Crohn's disease

M Gajendran, P Loganathan, AP Catinella… - Disease-a-month, 2018 - Elsevier
The term inflammatory bowel disease (IBD) refers principally to two major categories of
chronic relapsing inflammatory intestinal disorders: Crohn's disease (CD) and ulcerative …

Rebuilding the gut microbiota ecosystem

A Gagliardi, V Totino, F Cacciotti, V Iebba… - International journal of …, 2018 - mdpi.com
A microbial ecosystem in which bacteria no longer live in a mutualistic association is called
dysbiotic. Gut microbiota dysbiosis is a condition related with the pathogenesis of intestinal …

Epidemiology and risk factors for IBD

AN Ananthakrishnan - Nature reviews Gastroenterology & hepatology, 2015 - nature.com
IBD, comprising Crohn's disease and ulcerative colitis, is a chronic immunologically
mediated disease at the intersection of complex interactions between genetics, environment …

Intestinal permeability in inflammatory bowel disease: pathogenesis, clinical evaluation, and therapy of leaky gut

A Michielan, R D'Incà - Mediators of inflammation, 2015 - Wiley Online Library
The pathogenesis of inflammatory bowel disease (IBD) is multifactorial with data suggesting
the role of a disturbed interaction between the gut and the intestinal microbiota. A defective …

Western diet induces a shift in microbiota composition enhancing susceptibility to Adherent-Invasive E. coli infection and intestinal inflammation.

A Agus, J Denizot, J Thévenot, M Martinez-Medina… - Scientific reports, 2016 - nature.com
Recent advances have shown that the abnormal inflammatory response observed in CD
involves an interplay among intestinal microbiota, host genetics and environmental factors …

The role of diet in the aetiopathogenesis of inflammatory bowel disease

H Khalili, SSM Chan, P Lochhead… - Nature Reviews …, 2018 - nature.com
Crohn's disease and ulcerative colitis, collectively known as IBD, are chronic inflammatory
disorders of the gastrointestinal tract. Although the aetiopathogenesis of IBD is largely …

Diet and the intestinal microbiome: associations, functions, and implications for health and disease

LG Albenberg, GD Wu - Gastroenterology, 2014 - Elsevier
The mutual relationship between the intestinal microbiota and its mammalian host is
influenced by diet. Consumption of various nutrients affects the structure of the microbial …