Reactive oxygen species (ROS) are fundamental for macrophages to eliminate invasive
microorganisms. However, as observed in nonphagocytic cells, ROS play essential roles in …

Cardiovascular disease is a leading cause of death and reduced quality of life, proven by
the latest data of the Global Burden of Disease Study, and is only gaining in prevalence …

In a diabetic milieu high levels of reactive oxygen species (ROS) are induced. This
contributes to the vascular complications of diabetes. Recent studies have shown that ROS …

Background Many nutrients have powerful immunomodulatory actions with the potential to
alter susceptibility to coronavirus disease 2019 (COVID-19) infection, progression to …

Major reactive oxygen species (ROS)–producing systems in vascular wall include NADPH
(reduced form of nicotinamide adenine dinucleotide phosphate) oxidase, xanthine oxidase …

Acute respiratory distress syndrome (ARDS) caused by SARS-CoV-2 is largely the result of
a dysregulated host response, followed by damage to alveolar cells and lung fibrosis …

We report that cardiac fibroblasts (CFs) and mesenchymal progenitors are more hypoxic
than other cardiac interstitial populations, express more hypoxia-inducible factor 1α (HIF …

Accumulated evidence strongly indicates that oxidative stress, characterized by an
imbalance between reactive oxygen species (ROS) production and antioxidants in favor of …

Cardiovascular diseases are major contributors to global deaths and disability‐adjusted life
years, with hypertension a significant risk factor for all causes of death. The endothelium that …

The Global Burden of Disease Study identified cardiovascular risk factors as leading causes
of global deaths and life years lost. Endothelial dysfunction represents a pathomechanism …