PIWI-interacting RNAs: critical roles and therapeutic targets in cancer

J Zhou, H Xie, J Liu, R Huang, Y Xiang, D Tian, E Bian - Cancer Letters, 2023 - Elsevier
P-element-induced wimpy testis (PIWI)-interacting RNAs (piRNAs) are a novel class of small
regulatory RNAs (approximately 24–31 nucleotides in length) that often bind to members of …

miR‐203a—A multifaceted regulator modulating cancer hallmarks and therapy response

P Biswal, A Lalruatfela, SK Behera, S Biswal… - IUBMB …, 2024 - Wiley Online Library
MicroRNAs (miRNAs) are a class of noncoding RNAs of about 19–25 nucleotides, which
serve as critical modulators of various cellular and biological processes by target gene …

FDFT1 repression by piR-39980 prevents oncogenesis by regulating proliferation and apoptosis through hypoxia in tongue squamous cell carcinoma

T Chattopadhyay, B Mallick - Life Sciences, 2023 - Elsevier
Aim Tongue squamous cell carcinoma (TSCC) is one of the most aggressive tumors whose
underlying molecular mechanism remains elusive. Previous studies have identified piR …

[HTML][HTML] Non-coding RNAs in oral cancer: emerging roles and clinical applications

S Dey, B Biswas, A Manoj Appadan, J Shah, JK Pal… - Cancers, 2023 - mdpi.com
Simple Summary Oral cancer (OC) is one of the most prevalent cancers in the world. Despite
improvements in therapies, OC still has a poor survival rate of about 50%, with metastasis …

[HTML][HTML] Interactions of piRNAs with the mRNA of Candidate Genes in Esophageal Squamous Cell Carcinoma

A Rakhmetullina, A Akimniyazova, T Niyazova… - Current Issues in …, 2023 - mdpi.com
Recently, a database of human piRNAs (piwi-interacting RNAs) was created, which allows
the study of the binding of many piRNAs to the mRNAs of genes involved in many diseases …

The Mechanism and Clinical Application of Farnesyl Diphosphate Farnesyltransferase 1 in Cancer Metabolism

N Li, G Wang, M Guo, N Zhu, W Yu - Biochemical and Biophysical …, 2024 - Elsevier
Cancer poses a significant risk to human well-being. Among the crucial characteristics of
cancer is metabolic reprogramming. To meet the relentless metabolic needs, cancer cells …

TarpiD, a database of putative and validated targets of piRNAs

P Gupta, G Das, T Chattopadhyay, Z Ghosh… - Molecular …, 2023 - pubs.rsc.org
Piwi-interacting RNAs (piRNAs) are a novel class of 18–36 nts long small non-coding single-
stranded RNAs that play crucial roles in a wide array of critical biological activities besides …

A piRNA Portrait for Blood Cells of Healthy Donors and COVID-19 Patients

K Kondratov, AA Artamonov, Y Nikitin, A Velmiskina… - 2024 - preprints.org
The expression of non-coding RNAs varies greatly depending on the cell type and
physiological state. Changes in expression affect the regulatory properties of these …

Extraordinary Interactions of piRNAs with mRNA of Candidate Genes in Esophageal Squamous Cell Carcinoma

A Ivashchenko, A Rakhmetullina, A Akimniyazova… - 2023 - preprints.org
Recently, a database of human piRNAs has been created, which allows studying the
binding of many piRNAs to mRNAs of genes involved in many diseases, including cancer. In …

piRNA Profiling for COVID-19 Patients' and Healthy Donors' Blood Cells

K Kondratov, A Artamonov, Y Nikitin… - Available at SSRN … - papers.ssrn.com
Physiological condition and cell type have a major impact on non-coding RNA expression.
These molecules' regulatory characteristics are impacted by changes in expression. We …