[HTML][HTML] Flaxseed and pure secoisolariciresinol diglucoside, but not flaxseed hull, reduce human breast tumor growth (MCF-7) in athymic mice

J Chen, JK Saggar, P Corey, LU Thompson - The Journal of nutrition, 2009 - Elsevier
Previous studies have shown that dietary flaxseed (FS) can reduce the growth of established
human breast tumors in athymic mice with low circulating estrogen concentrations. In this …

Availability of bioactive flax lignan from foods and supplements

TJ Tse, Y Guo, YY Shim, SK Purdy, JH Kim… - Critical Reviews in …, 2023 - Taylor & Francis
Hyperlipidemia, high levels of blood lipids including cholesterol and triglycerides, is a major
risk factor for cardiovascular disease. Traditional treatments of hyperlipidemia often include …

[PDF][PDF] Evaluation of flaxseed formulation as a potential therapeutic agent in mitigation of dyslipidemia

S Saxena, C Katare - Biomedical journal, 2014 - biomedj.cgu.edu.tw
Background: Cardiovascular diseases (CVDs) are an increasing health problem all over the
world. The search for natural hypolipidemic agents that can be used besides the synthetic …

Oral pharmacokinetics of enriched secoisolariciresinol diglucoside and its polymer in rats

X Yang, Y Guo, TJ Tse, SK Purdy… - Journal of Natural …, 2021 - ACS Publications
Secoisolariciresinol diglucoside (SDG) is the principal lignan of flaxseed and precursor of its
aglycone, secoisolariciresinol (SECO), and the mammalian lignans enterolactone (EL) and …

Linoorbitides and enterolactone mitigate inflammation-induced oxidative stress and loss of intestinal epithelial barrier integrity

AA Almousa, F Meurens, ES Krol, J Alcorn - International …, 2018 - Elsevier
Barrier integrity dysfunction and oxidative stress are considered hallmarks of inflammatory
bowel disease (IBD) pathogenesis. Their mitigation continues to be a drug discovery target …

Flax mucilage and barley beta-glucan aerogels obtained using supercritical carbon dioxide: Application as flax lignan carriers

LM Comin, F Temelli, MDA Saldaña - Innovative Food Science & Emerging …, 2015 - Elsevier
Flax lignan, secoisolariciresinol diglucoside (SDG), has been implicated in the prevention of
hormonally related cancers and other diseases. Polysaccharide aerogels, dried using …

Influence of flaxseed lignan supplementation to older adults on biochemical and functional outcome measures of inflammation

Y Di, J Jones, K Mansell, S Whiting… - Journal of the …, 2017 - Taylor & Francis
Evidence from the literature suggests that dietary flaxseed lignans have the ability to
modulate inflammation, which is recognized as the underlying basis of multiple chronic …

[PDF][PDF] Preparation of flaxseed for lignan determination by gas chromatography-mass spectrometry method

H SaraJliJa, N ČukelJ, D NoVotNi, G Mršić… - Czech J. Food …, 2012 - academia.edu
Preparation of Flaxseed for Lignan Determination by Gas Chromatography-Mass Spectrometry
Method Page 1 45 Czech J. Food Sci. Vol. 30, 2012, No. 1: 45–52 Preparation of Flaxseed for …

7-Hydroxymatairesinol improves body weight, fat and sugar metabolism in C57BJ/6 mice on a high-fat diet

G Biasiotto, I Zanella, F Predolini, I Archetti… - British Journal of …, 2018 - cambridge.org
7-Hydroxymatairesinol (7-HMR) is a plant lignan abundant in various concentrations in plant
foods. The objective of this study was to test HMRLignan™, a purified form of 7-HMR, and …

Atherosclerosis prevention and treatment in children and adolescents

FLC Oliveira, RV Patin… - Expert Review of …, 2010 - Taylor & Francis
The atherosclerotic process starts in childhood and studies show its development in fetuses.
Clinical manifestation often occurs only in the sixth decade of life. Adolescence is a critical …