Inhaled corticosteroids (ICS) are the mainstay of treatment for asthma, but their role in
chronic obstructive pulmonary disease (COPD) is debated. Recent randomised controlled …

Phosphodiesterase (PDE) 4 inhibitors prevent the metabolism of cyclic adenosine
monophosphate, thereby reducing inflammation. Inhaled PDE4 inhibitors aim to restrict …

Abstract The Veterans Health Administration (VHA) is the largest integrated healthcare
system in the United States (US) providing healthcare to an increasing number of middle …

The development of molecules embedding two distinct pharmacophores acting as
muscarinic antagonists and β2 agonists (MABAs) promises to be an excellent opportunity to …

Cuproptosis, a novel mode of cell death, is strongly associated with a variety of diseases.
However, the contribution of cuproptosis to the onset or progression of chronic obstructive …

Background. The effective‐component compatibility of Bufei Yishen formula III (ECC‐BYF III)
with 5 ingredients (ginsenoside Rh1, astragaloside, icariin, nobiletin, and paeonol) has …

Background: Chronic obstructive pulmonary disease (COPD) inflammatory endotypes are
associated with different airway microbiomes. We used quantitative polymerase chain …

Objective Accurate biomarkers for evaluating mortality rates in patients with chronic
obstructive pulmonary disease (COPD) remain scarce. This study aimed to explore the …

Background. Chronic obstructive pulmonary disease (COPD) is becoming a major public
health burden worldwide. It is urgent to explore more effective and safer treatment strategy …

Chronic obstructive pulmonary disease (COPD) is a complex disease, and its pathogenesis
is influenced by genetic factors. This study aimed to evaluate the role of IL5RA genetic …