Apoptosis is a sequential order of cell death occurring regularly to ensure a homeostatic
balance between the rate of cell formation and cell death. However, a misplaced of this …

Various physiological processes involve appropriate tissue developmental process and
homeostasis-the pathogenesis of several diseases connected with deregulatory apoptosis …

Apoptosis, the cell's natural mechanism for death, is a promising target for anticancer
therapy. Both the intrinsic and extrinsic pathways use caspases to carry out apoptosis …

Abstract Phosphatidylinositol 3-kinases (PI3Ks) are crucial coordinators of intracellular
signalling in response to the extracellular stimulators. Hyperactivation of PI3K signalling …

Alcohol-related liver disease is the most prevalent type of chronic liver disease worldwide,
accounting for 30% of hepatocellular carcinoma (HCC) cases and HCC-specific deaths …

Apoptosis is a highly-regulated, active process of cell death involved in development,
homeostasis and aging. Dysregulation of apoptosis leads to pathological states, such as …

Despite advances in neurosurgical techniques and radio-/chemotherapy, the treatment of
brain tumors remains a challenge. This is particularly true for the most frequent and fatal …

Alcohol is inextricably linked with the digestive system. It is absorbed through the gut and
metabolised by hepatocytes within the liver. Excessive alcohol use results in alterations to …

Gambogic acid (GA), a kind of dry resin secreted by the Garcinia hanburyi tree, is a natural
active ingredient with various biological activities, such as anti-cancer, anti-inflammatory …

Graviola (Annona muricata) is a small deciduous tropical evergreen fruit tree, belonging to
the Annonaceae family, and is widely grown and distributed in tropical and subtropical …